This NeuroView assesses the interplay among exposome, One Health, and brain capital in health and disease. Physical and social exposomes affect brain health, and green brain skills are required for environmental health strategies. Ibanez et al. address current gaps and strategies needed in research, policy, and technology, offering a road map for stakeholders.
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http://dx.doi.org/10.1016/j.neuron.2024.04.016 | DOI Listing |
Alzheimers Dement
December 2024
Department of Medicine, Duke University, Durham, NC, USA.
Background: The GI tract is home to approximately 70% of the body's immune cells, >100 million enteric neurons, and ∼40 trillion bacteria. This co-localization of myriad immune, neural and bacterial cells creates complex interactions that regulate almost every tissue in the body, including the brain. Importantly, peripheral and GI inflammation occur in neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer (AD) contributing to gut brain axis.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
An Pediatr (Engl Ed)
December 2024
Comité de Salud Medioambiental, Global Alliance for Rewilding Child and Adolescent Health, Asociación Española de Pediatría, Madrid, Spain; Pediatric Environmental Health Speciality Unit (PEHSU), Hospital Clínico Universitario Virgen de la Arrixaca, Universidad de Murcia. Murcia, Spain. Electronic address:
Breast Cancer Res
December 2024
Biostatistics Unit, The Cyprus Institute of Neurology and Genetics, 6 Iroon Avenue, 2371 Ayios Dometios, Nicosia, Cyprus.
Background: The 313-variant polygenic risk score (PRS) provides a promising tool for clinical breast cancer risk prediction. However, evaluation of the PRS across different European populations which could influence risk estimation has not been performed.
Methods: We explored the distribution of PRS across European populations using genotype data from 94,072 females without breast cancer diagnosis, of European-ancestry from 21 countries participating in the Breast Cancer Association Consortium (BCAC) and 223,316 females without breast cancer diagnosis from the UK Biobank.
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