AI Article Synopsis
- Strain TC023 is a new species of Gram-positive, anaerobic bacteria discovered in a heart failure mouse model, characterized by its long, rod shape and spore-forming ability.
- It formed distinct greyish-white colonies on a specific growth medium and showed close genetic similarities to existing strains MMM721 and MOL361 based on 16S rRNA gene sequencing.
- Genomic analysis revealed that TC023 has unique DNA characteristics, leading to its classification as a novel species within its genus, with TC023 designated as the type strain.
Article Abstract
Strain TC023, a Gram-positive, long, rod-shaped, spore-forming anaerobe, was isolated from the faeces of a heart failure mouse model. The strain formed greyish-white coloured colonies with a convex elevation on brain-heart infusion medium supplemented with 0.1 % sodium taurocholate, incubated at 37 °C for 2 days. Taxonomic analysis based on the 16S rRNA gene sequence showed that TC023 belonged to the genus , and was closely related to MMM721 (97.6 %) and MOL361 (97.4 %). The whole genome of the strain has a G+C content of 37.3 mol%. The average nucleotide identity and genome-to-genome distance between TC023 and MMM721 were 77.6 % and 24.3 %, respectively, and those with MOL361 were 75.4 % and 24.3 %, respectively. These genotypic, phenotypic, and biochemical analyses indicated that the isolate represents a novel species in the genus , and the name sp. nov. is proposed. The type strain is TC023 (RIMD 2002001=TSD 372).
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165905 | PMC |
| http://dx.doi.org/10.1099/ijsem.0.006379 | DOI Listing |
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