Maternal anemia and red blood cell requirements in 72 women undergoing intrapartum treatment (EXIT) procedure.

Front Med (Lausanne)

Goethe University Frankfurt, University Hospital, Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Frankfurt, Germany.

Published: April 2024

AI Article Synopsis

  • The EXIT (Ex-utero Intrapartum Treatment) procedure allows safe fetal airway management during childbirth while maintaining blood flow between the mother and fetus, but carries risks such as significant blood loss and increased transfusion needs.
  • A study reviewed data from hospitalized women who underwent the EXIT procedure over a 15-year period, focusing on anemia prevalence, hemorrhage, and blood transfusions.
  • Findings showed nearly half the women had anemia during pregnancy, with 11.1% experiencing postpartum hemorrhage, highlighting the need for effective anemia management and blood conservation strategies during this complex procedure.

Article Abstract

Background: The intrapartum treatment (EXIT) allows to ensure fetal airway while keeping uteroplacental circulation. However, EXIT may become a life-threatening procedure due to the increased risk of uterine atony or placenta abruption with increased peripartum blood losses and increased transfusion rates. We aim to review maternal anemia prevalence and transfusion requirements in women undergoing EXIT procedure.

Methods: Using data from the Federal German Statistical Office hospitalized women undergoing EXIT procedure between January 1st 2006 and December 31st 2021 were included. The prevalence of anemia, peripartum hemorrhage, comorbidities and administration of red blood cells (RBC) were analyzed.

Results: In total, 72 women underwent EXIT procedure with a median age of 31 years (26;33.5). In 43.1% EXIT was conducted at 34-36 weeks of gestational age. "Anemia during pregnancy" was present in 47.2%, "anemia due to acute bleeding" in 25.0% and "iron deficiency anemia" in 15.3%. Postpartum hemorrhage occurred in 11.1%. RBCs were transfused in 15.3% of all women. Most women required 1-5 units of RBCs.

Conclusion: Despite the rarity of this procedure, anemia management and blood conservation strategies in order to reduce the need for RBC transfusion are highly important in women undergoing EXIT procedure.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076707PMC
http://dx.doi.org/10.3389/fmed.2024.1353405DOI Listing

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