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http://dx.doi.org/10.1136/bcr-2023-259227DOI Listing

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Combining Paracentral Acute Middle Maculopathy and Peripapillary Fluid as Biomarkers in Anterior Ischemic Optic Neuropathy.

Am J Ophthalmol

December 2024

Department of Ophthalmology (O.N.K., M.S.H., L.L., Y.S., A.K.W., S.H., S.H.), Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine (O.N.K., M.S.H., L.L., A.K.W., S.H., L.T., S.H.), University of Copenhagen, Copenhagen, Denmark.

Purpose: To determine if paracentral acute middle maculopathy (PAMM) and peripapillary intraretinal and subretinal fluid (IRF/SRF) could help distinguish between arteritic anterior ischemic optic neuropathy (A-AION) and nonarteritic AION (NA-AION) at an early stage.

Design: Nested prospective cross-sectional diagnostic accuracy study.

Methods: This study used single-center optical coherence tomography (OCT) data from 8 patients with A-AION and 24 patients with NA-AION from two prospective cross-sectional studies with consecutive sampling (ClinicalTrials.

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Background: Bilateral optic neuritis associated with optic disc swelling is a common feature of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). However, extensive deep retinal haemorrhages have not been described in the context of MOG-associated optic neuritis. Here, we report a case of infectious mononucleosis with marked binocular peripapillary and perivascular haemorrhages as well as extensive deep retinal haemorrhages in the presence of MOGAD.

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Article Synopsis
  • * A literature review was conducted using databases like PubMed and Google Scholar to gather evidence on the causes and differentiation methods for both conditions.
  • * Techniques such as Fundus fluorescein angiography, optical coherence tomography, and MRI help distinguish between the two, and in some cases, more invasive procedures like lumbar punctures may be necessary.
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Background: Macular retinoschisis (MRS) and myopic macular neovascularization (mMNV) are both potentially blinding complications of high myopia. In this case report, we highlight the progression of MRS after intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment for mMNV, as well as an extensive review of the literature on this topic.

Case Description: A 49-year-old woman presented with two weeks of recent onset blurring and metamorphopsia in her right eye.

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