Lettuce, a globally consumed nutritious vegetable, is often linked to concerns regarding pesticide residues. To address this issue, we conducted field trials and utilized dynamiCROP modeling to examine the uptake, distribution, translocation, and dissipation of five pesticides (λ-cyhalothrin, difenoconazole, acetamiprid, dimethomorph, and β-cypermethrin) commonly detected in lettuce. At harvest, pesticides residues were below the maximum residue limits (MRLs) at 0.05, 0.39, 0.047, 0.72, and 0.072 mg kg, respectively. Simulation results elucidated distinct behaviors of the pesticides following application to lettuce foliage across various compartments. However, all pesticides exhibited a common dissipation trend, initially stabilizing or increasing before gradually declining. For all five pesticides, the largest contribution of residues on lettuce leaves came from the leaf surface during the early period after application, and from the soil in the long term. Health risk assessments indicated negligible risks associated with consuming lettuce containing these pesticides, both in the short and long term.
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http://dx.doi.org/10.1016/j.foodchem.2024.139510 | DOI Listing |
Sci Rep
January 2025
Department of Clinical Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
The study aimed to compare the oxidative stress status in the kidney tissue of rats treated with paraquat and nanoparaquat. The levels of oxidative stress markers, including malondialdehyde (MDA), total antioxidant capacity (TAC), and thiol groups (TTG), were measured in the kidney tissue samples. A total of forty male Wistar rats were randomly assigned to eight groups, each consisting of five rats: a control group, a paraquat (PQ) group, an N-acetylcysteine (NAC) group, groups receiving nanoparaquat α and β (α and β), groups receiving PQ and NAC (PQ + NAC), and groups receiving nanoparaquat α and β with NAC (+ NACα and β).
View Article and Find Full Text PDFActa Trop
December 2024
Centro de Investigación en Alimentación y Desarrollo, A. C. (CIAD), 83304 Hermosillo, Sonora, Mexico. Electronic address:
Ticks are significant ectoparasites that transmit a variety of pathogens, leading to serious human and animal diseases, including Lyme disease, Rocky Mountain spotted fever, anaplasmosis and many others. The emergence of acaricide resistance in hard ticks presents a formidable challenge for public health and livestock management, exacerbated by the increasing incidence of tick-borne diseases and associated economic losses, estimated at $20 billion annually in the livestock sector alone. This review examines the mechanisms underlying acaricide resistance, focusing on genetic mutations, metabolic detoxification processes, and behavioral adaptations in tick populations.
View Article and Find Full Text PDFMol Cell Proteomics
December 2024
Department of Pharmacology and Toxicology, University of Texas Medical Branch.
Pyrethroid pesticides have been associated with neurodevelopmental disorders including attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). While behavioral effects of pyrethroid exposure have been previously reported, the underlying mechanisms remain unclear. Here, we hypothesized that exposure to deltamethrin (DM), a widely used pyrethroid pesticide known for its neurotoxicity during early developmental stages, induces brain dysfunction through alterations in brain-derived extracellular vesicle (BDEV) signaling.
View Article and Find Full Text PDFEnviron Res
December 2024
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois Chicago.
Background: Previous studies have demonstrated associations of persistent organic pollutants (POPs) with sex-related hormones; however, findings were inconsistent. Sex-specific impacts and pathways through which adiposity influences associations are not completely understood. We sought to evaluate sex-specific associations of POPs serum concentration with sex-related hormones and to explore pathways through which adiposity may modify associations.
View Article and Find Full Text PDFJ Nutr
December 2024
Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Fertility Center, Vincent Department of Obstetrics and Gynecology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:
Background: We previously reported that the intake of fruits and vegetables (FV) known to have high pesticide contamination in the US food supply is related to lower sperm counts. Whether the same is true for ovarian reserve is unknown.
Methods: Participants were 633 females, 21-45 years, presenting to an academic fertility center.
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