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http://dx.doi.org/10.1056/NEJMc2404154 | DOI Listing |
Environ Sci Technol
January 2025
Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, Queensland 4102, Australia.
Humans are constantly exposed to micro- and nanosized plastics (MNPs); however, there is still limited understanding of their fate within the body, partially due to limitations with current analytical techniques. The current study assessed the appropriateness of pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) analysis for the quantification of a range of polymers in human blood. An extraction protocol that reduced matrix interferences (false positives) of polyethylene (PE) and polyvinyl chloride (PVC) was developed and validated.
View Article and Find Full Text PDFNanoImpact
January 2025
Géosciences Rennes, CNRS/Université Rennes, 263 av. Général Leclerc, 35000 Rennes, France.
Nanoplastics (NPs) are gaining increasing attention due to their widespread distribution and potential environmental and biological impacts. Spanning a variety of ecosystems - from soils and rivers to oceans and polar ice - NPs interact with complex biological and geochemical processes, posing risks to organisms across multiple trophic levels. Despite their growing presence, understanding the behavior, transport, and toxicity of nanoplastics remains challenging due to their diverse physical and chemical properties as well as the heterogeneity of environmental matrices.
View Article and Find Full Text PDFJ Xenobiot
December 2024
Department of Chemistry "Giacomo Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy.
Skin represents an effective barrier against the penetration of external agents into the human body. Nevertheless, recent research has shown that small particles, especially in the nanosized range, can not only penetrate through the skin but also work as vectors to transport active molecules such as contrast agents or drugs. This knowledge has opened new perspectives on nanomedicine and controlled drug delivery.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Key Laboratory of Bio-resources and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China. Electronic address:
Microplastics (MPs, 1 µm-5 mm) and nanoplastics (NPs, < 1 µm), collectively termed micro(nano)plastics (MNPs), are pervasive airborne pollutants with significant ecological risks. Birds, recognized as bioindicators, are particularly vulnerable to MNP exposure, yet the extent and risks of MNP pollution in bird lungs remain largely unexplored. This study assessed MP exposure in bird lungs of 51 species and NP exposure in the lungs of five representative species using laser direct infrared (LDIR) and pyrolysis gas chromatography-mass spectrometry (Py-GC-MS) techniques, respectively.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
January 2025
Arbeitsgemeinschaft Nachhaltigkeit in der Dermatologie (AGN) e.V., Freiburg, Germany.
Hazards to human and planetary health are present at every stage of the plastic life cycle, yet plastic production is projected to triple by 2060. This review focuses on three key areas: the life cycle of plastic, the impact of microplastics and their associated chemicals, along with recommendations to reduce plastic use. In dermatology, micro- and nanoplastics are especially problematic as they are present in over 90% of personal care products.
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