AI Article Synopsis

  • A 19-year-old woman with asthma experienced confusion after a near-drowning incident two weeks prior to her hospital admission.
  • Medical tests revealed severe thrombocytopenia and microangiopathic hemolytic anemia (MAHA), leading to a high suspicion of thrombotic thrombocytopenic purpura (TTP) as the diagnosis.
  • The patient underwent treatment for TTP, including plasma exchange and rituximab, and showed improvement during a year of follow-up, although she did not achieve remission.

Article Abstract

A 19-year-old woman with a history of asthma presented with acute confusion following a near-drowning event 2 weeks prior to admission. She was found to have severe thrombocytopenia and microangiopathic hemolytic anemia (MAHA). The treatment for thrombotic thrombocytopenic purpura (TTP) was started on the day of admission due to high clinical suspicion. Subsequent workup confirmed a diagnosis of TTP with no clear etiology except the near-drowning incident. TTP following a near-drowning event has never been reported in the literature. Furthermore, she developed refractory TTP that required reinitiation of therapeutic plasma exchange and rituximab. After discharge, the patient had been doing well over a year of follow-up without remission.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11075175PMC
http://dx.doi.org/10.5414/CNCS111301DOI Listing

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