AI Article Synopsis

  • MRCP is an imaging technique essential for studying pancreaticobiliary diseases, and this study tested how three oral contrast agents (date syrup, hematinic syrup, and pineapple juice) affect image quality.
  • The study involved 90 participants divided into three groups, each ingesting different oral contrasts before being scanned using 1.5 Tesla MRI, measuring signal-to-noise and contrast-to-noise ratios.
  • Results showed that while all three agents improved image quality, pineapple juice had the best signal-to-noise ratio, followed by date syrup and hematinic syrup, with no adverse effects reported from the participants.

Article Abstract

Introduction: Magnetic resonance cholangiopancreatography (MRCP) is an imaging technique that has advanced over the past few years. It still plays a crucial role in the study of numerous pancreaticobiliary diseases. This study aimed to evaluate the effects of hematinic syrup, date syrup, and pineapple juice on MRCP image quality.

Methodology: This study involved a total of 90 participants, distributed evenly among three groups, with each group comprising 30 patients. Negative oral contrast solutions containing paramagnetic substances like Mn+2 and Fe+3, such as pineapple juice, date syrup, and hematinic syrup were imaged by 1.5 Tesla (T) magnetic resonance imaging (MRI) with T2-weighted (T2W) and MRCP sequences. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were computed. Ninety patients underwent MRCP 20-30 min after ingestion of 100 mL of date syrup, 30 ml of hematinic syrup diluted to 200 ml of water, and 200 mL of pineapple juice. MRCP images were taken to visualize various pancreaticobiliary structures (bile duct, stomach, and duodenum).

Results: The in vitro evaluation of the solutions showed that date syrup and hematinic syrup were hypointense in T2W sequences. The images obtained showed no significant difference in the CNR between the three solutions. However, the SNR was significantly higher for pineapple juice compared to date syrup and hematinic syrup in T2W and MRCP sequences. Images acquired post-administration of the oral contrast agents significantly improved the gastrointestinal tract signal suppression and increased visibility of the pancreaticobiliary structures (bile duct, stomach, and duodenum). No adverse events were observed among the participants.

Conclusion: Pineapple juice was the best contrast agent. However, date syrup and hematinic syrup can also be used to improve the imaging quality.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11074849PMC
http://dx.doi.org/10.7759/cureus.57769DOI Listing

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