En plaque meningioma is a rare type of meningioma characterized by an infiltrative nature, sheet-like growth, and at times invading the bone. We report here a case of en plaque meningioma. The patient was a 66-year-old woman presenting with headache and painful bilateral proptosis. Cerebral magnetic resonance imaging revealed a bilateral en plaque meningioma showed as a bilateral hyperostotic of greater wing sphenoid bone associated with bilateral thickening and enhancement of the dura in the anterior temporal area and the retroclival region invading bilaterally the cavernous sinus, the prechiasmatic portion of the optic nerve, and the lateral rectus muscle of the orbit through the superior orbital fissure causing bilateral exophthalmia. Due to invasion of the cavernous sinus and the orbital apex, a subtotal but extensive removal combined with bony decompression of the cranial nerves at the superior orbital fissure and optic canal followed by adjuvant radiotherapy frequently produces good functional and cosmetic results, and over a 3-year period, follow-up magnetic resonance imaging scans showed no obvious signs of recurrence.
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http://dx.doi.org/10.1177/2050313X241252340 | DOI Listing |
J Neuropathol Exp Neurol
December 2024
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Rubinstein-Taybi syndrome (RTS) is a congenital disorder with characteristic clinical manifestations. In the vast majority of cases, it is caused by mutations of the gene encoding the transcriptional co-activator cAMP-response element binding protein (CBP)-binding protein (CREBBP). It has been thought to be a tumor predisposition syndrome as RTS patients have an increased risk of developing tumors including meningiomas.
View Article and Find Full Text PDFInt J Surg Case Rep
December 2024
Department of Pathology, Damascus University, Damascus, Syria. Electronic address:
Introduction: Meningiomas en Plaque (MEP) represents a rare subtype, typically affecting females and seen in the fifth decade of life, with proptosis as a common presenting symptom, posing both diagnostic and surgical challenges.
Case Presentation: A 55-year-old right-handed male presented with right hemiplegia, headache, vomiting, and frequent seizures. Neurological examination showed reduced visual acuity and right-sided exophthalmos.
Curr Med Imaging
December 2024
Department of Vascular Neurosurgery, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", 14267, Mexico City, Mexico.
Background: Castleman disease (CD) is a rare lymphoproliferative disorder, with intracranial involvement being exceedingly rare. Unicentric Castleman disease (UCD) is typically benign and localized, but its presentation can mimic other intracranial pathologies, complicating diagnosis.
Case Description: We reported a 52-year-old woman who presented with progressive headaches and language disturbances.
J Clin Neurosci
December 2024
Department of Radiology, Gangnam Severance Hospital, Yonsei University, College of Medicine, Seoul, Republic of Korea. Electronic address:
Spinal cord meningiomas are typically benign, rare tumors that pose clinical challenges owing to their location and potential for spinal cord compression. This study aimed to assess the radiological features of spinal cord meningiomas and the key factors associated with their recurrence. We conducted a retrospective, single-institution study on 67 patients with pathologically confirmed spinal cord meningiomas who were surgically treated between January 2016 and December 2023.
View Article and Find Full Text PDFCancer Treat Res Commun
November 2024
Department of Otolaryngology - Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Alma Mater Studiorum - Università di Bologna, Italy. Electronic address:
Objective: To review the published cases of meningioma en plaque of the temporal bone (TB-MEP), to gather evidence on the clinical assessment and management of this rare entity.
Methods: Following PRISMA statement recommendations, 383 abstracts were screened independently by two authors. Inclusion criteria were articles of human patients affected by TB-MEP; English or Italian language; availability of the abstract articles unrelated to TB-MEP, guidelines and systematic reviews were excluded.
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