Blockchain technology has become crucial in improving the privacy and security of enterprise applications in the cyber world. However, scalability has become a significant concern for researchers in large organizations, especially those with complex hierarchies and access privileges. As a result, the existing models and consensus algorithms suffer from various issues. Medical centers and healthcare providers are particularly affected by this problem due to the vast amount of data, making it a critical weakness of traditional database management systems. To address this issue, the authors propose a hierarchical model within the Hyperledger Fabric enterprise application, focusing on the healthcare sector as a use case. This model includes multiple organizations at different levels of the hierarchy, such as hospitals, hospital governance, and insurance companies. The initial implementation of this model includes two levels of hierarchy, demonstrating networks of hospitals joining an insurance company. The primary objective of the experiment is to test and improve the network's performance using this model. The model's performance is evaluated by manipulating and scaling environmental factors such as the number of organizations, transaction numbers, channels, block intervals, and block sizes. The benchmarking tool used for this assessment is Hyperledger Caliper, which measures indicators such as success and failure rates, throughput, and latency. Currently, the research focuses only on testing the model's scalability using patient data.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11073480 | PMC |
http://dx.doi.org/10.30953/bhty.v7.295 | DOI Listing |
PM R
January 2025
Department of Psychology, University of Virginia, Charlottesville, Virginia, USA.
Background: Research on older adults who sustain a traumatic brain injury (TBI) has predominantly been on civilian, nonveteran populations. Military populations experience higher rates of TBI and often experience the additive effects of TBI and other comorbid disorders, including posttraumatic stress disorder and/or substance use that may increase disability over time.
Objective: To investigate predictors of functional independence trajectories over the 5 years after TBI in veterans 55 years or older at injury.
Leadersh Health Serv (Bradf Engl)
January 2025
Department of Management, University of Chittagong, Chittagong, Bangladesh.
Purpose: This study aims to test the nurses' authentic leadership's direct and indirect impact on job satisfaction and intent to stay through work-to-family conflict (WFC) in health-care organizations.
Design/methodology/approach: Data were gathered at three different time points from 262 nurses employed in public hospitals across Bangladesh. Hierarchical regression analysis using structural equation modeling and PROCESS Macro were used to test the hypotheses.
Cochrane Database Syst Rev
January 2025
Department of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Rationale: Osteoporosis is an abnormal reduction in bone mass and bone deterioration, leading to increased fracture risk. Alendronate belongs to the bisphosphonate class of drugs, which inhibit bone resorption by interfering with the activity of osteoclasts (bone cells that break down bone tissue). This is an update of a Cochrane review first published in 2008.
View Article and Find Full Text PDFRecent advances in generative modeling enable efficient sampling of protein structures, but their tendency to optimize for designability imposes a bias toward idealized structures at the expense of loops and other complex structural motifs critical for function. We introduce SHAPES (Structural and Hierarchical Assessment of Proteins with Embedding Similarity) to evaluate five state-of-the-art generative models of protein structures. Using structural embeddings across multiple structural hierarchies, ranging from local geometries to global protein architectures, we reveal substantial undersampling of the observed protein structure space by these models.
View Article and Find Full Text PDFGiven the same external input, one's understanding of that input can differ based on internal contextual knowledge. Where and how does the brain represent latent belief frameworks that interact with incoming sensory information to shape subjective interpretations? In this study, participants listened to the same auditory narrative twice, with a plot twist in the middle that dramatically shifted their interpretations of the story. Using a robust within-subject whole-brain approach, we leveraged shifts in neural activity between the two listens to identify where latent interpretations are represented in the brain.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!