AI Article Synopsis
- Researchers found two strains of bacteria originally thought to be Providencia rettgeri, but genome analysis revealed they are distinct enough to be classified as a new species named Providencia xianensis.
- The new strains demonstrate multidrug resistance and are resistant to last-resort antibiotics, indicating a serious public health threat.
- Their discovery highlights the need for increased monitoring and proactive measures to combat the spread of these emerging, drug-resistant pathogens.
Article Abstract
Providencia genus is known to harbor certain opportunistic pathogens capable of causing human infections. Here, we report two strains of multidrug-resistant bacteria initially identified as Providencia rettgeri by mass spectrometry, but genome analysis revealed their ANI (79.84-84.20%) and dDDH (21.1-25.6%) values to fall below the accepted species threshold for known Providencia species. We therefore propose that these isolates be recognized as a novel species, Providencia xianensis sp. nov. Alarmingly, both strains, isolated from locations far apart, exhibited resistance to last-resort antibiotics, indicating their possible wide distribution, underscoring the urgency for immediate attention and enhanced surveillance for this emerging multidrug-resistant pathogen.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11271419 | PMC |
| http://dx.doi.org/10.1007/s10096-024-04821-y | DOI Listing |
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