A vital heuristic used when making judgements on whether audio-visual signals arise from the same event, is the temporal coincidence of the respective signals. Previous research has highlighted a process, whereby the perception of simultaneity rapidly recalibrates to account for differences in the physical temporal offsets of stimuli. The current paper investigated whether rapid recalibration also occurs in response to differences in central arrival latencies, driven by visual-intensity-dependent processing times. In a behavioural experiment, observers completed a temporal-order judgement (TOJ), simultaneity judgement (SJ) and simple reaction-time (RT) task and responded to audio-visual trials that were preceded by other audio-visual trials with either a bright or dim visual stimulus. It was found that the point of subjective simultaneity shifted, due to the visual intensity of the preceding stimulus, in the TOJ, but not SJ task, while the RT data revealed no effect of preceding intensity. Our data therefore provide some evidence that the perception of simultaneity rapidly recalibrates based on stimulus intensity.
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http://dx.doi.org/10.1163/22134808-bja10121 | DOI Listing |
BMJ Open
December 2024
Department of Anesthesiology, Henan Provincial Chest Hospital & Chest Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Introduction: Chronic post-thoracotomy pain (CPTP) is a persistent and disabling condition affecting a significant proportion of patients after thoracotomy and posing a challenge for clinicians, despite advances in surgical and pain management strategies. Esketamine, the S-enantiomer of ketamine, has emerged as a promising therapeutic agent for various pain conditions, with evidence for its effectiveness in alleviating acute and chronic pain. This systematic review and meta-analysis will be conducted to assess the efficacy of esketamine in treating CPTP, and evaluate its effectiveness in reducing pain intensity, improving functional outcomes, and reducing opioid consumption, as well as its adverse effects.
View Article and Find Full Text PDFSci Rep
December 2024
Kombolcha Institute of Technology, Wollo University, Dessie, Ethiopia.
Alcohol-based fuels have shown high compatibility with spark-ignition (SI) engines, which require improvements in fuel efficiency and emissions reduction to meet modern environmental standards. While extensive research has been conducted on ethanol and other lower-order alcohols, there has been comparatively limited investigation into higher-order alcohols like butanol and pentanol as fuel alternatives. Previous studies on pentanol-gasoline blends in SI engines have demonstrated improved engine performance and reduced emissions.
View Article and Find Full Text PDFNeuro Endocrinol Lett
December 2024
Department of Psychiatry, Faculty of Medicine and Dentistry, Palacky University in Olomouc, Czech Republic.
Objective: This article focuses on utilizing therapeutic letters within group schema therapy-an innovative therapeutic approach that integrates elements from various therapeutic disciplines. The primary aim is to explore how therapeutic letters can enhance the therapeutic process and support the treatment of patients.
Methods: To achieve this objective, we conducted a narrative literature review centred on schema therapy and using therapeutic letters as a therapeutic strategy.
Front Ophthalmol (Lausanne)
December 2024
Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
Purpose: Thyroid eye disease (TED) primarily occurs in hyperthyroid patients, sometimes resulting in poor visual prognosis. Although other autoimmune diseases have been reported to be associated with serum programmed cell death 1 (PD-1), the relationship with TED remains unknown. This study investigated the relationship between TED and immune checkpoint molecules.
View Article and Find Full Text PDFJ Endod
December 2024
Department of Endodontics, Nihon University School of Dentistry, 1-8-13, Kanda-surugadai, Chiyoda-ku, Tokyo, 101-8310, Japan; Division of Advanced Dental Treatment, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan.
Introduction: We have recently reported the clinical efficacy of mirogabalin for occlusal pain due to post-traumatic trigeminal neuropathic pain (PTTN-occlusal pain) after endodontic treatment according to the International Classification of Orofacial Pain criteria. This study aimed to determine the mirogabalin administration period and timing of dose reduction and suspension for treating this condition based on managing a certain number of cases.
Methods: Patients diagnosed with PTTN-occlusal pain after or during endodontic treatment were included in the study.
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