AI Article Synopsis
- CDI, caused by Clostridioides difficile, leads to healthcare-associated diarrhea, and fidaxomicin (FDX) is suggested to be more effective and cost-efficient than vancomycin (VAN) for treatment.
- The study analyzed data from University Hospital Cologne, focusing on the costs and recurrence rates of CDI for both treatments, and found total average costs of €32,901 for non-recurrent cases and €10,952 for recurrent cases.
- The budget impact analysis revealed a potential cost savings of €1,303 favoring FDX over VAN, highlighting the need for future research on treating specific groups like refractory CDI patients.
Article Abstract
Background: is the most common cause of healthcare-associated diarrhea. Research suggests that treating infections (CDI) with fidaxomicin (FDX) is more effective than vancomycin (VAN), with potential cost savings. The objective was to calculate the budget impact of FDX treatment compared to VAN from a German payer perspective.
Research Design And Methods: The analysis used real-world data of patients discharged from University Hospital Cologne between Jan-01-2018 and Dec-31-2019. We identified recurrent and non-recurrent CDI cases and calculated direct treatment costs based on G-DRG flat rates. To calculate average costs per treatment and the budget impact, recurrence probabilities for VAN and FDX were taken from published evidence (28-day and 90-day scenarios).
Results: Totally, 475 cases were analyzed, thereof 421 non-recurrent, causing mean costs of €32,901 per case (95% CI: 27.752-38.050). Thirty-two patients experienced a recurrence within 28 days, yielding mean costs of €10,952 (95% CI: 5.627-16.277) for their additional hospital stay. The resulting budget impact was €1,303 (95% CI: 670-1.937) in favor of FDX, ranging from €148.34 to €2,190.30 in scenario analyses.
Conclusion: The analysis indicates FDX treatment can lead to cost savings compared to VAN. Future research should focus on specific patient groups, such as refractory CDI patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14737167.2024.2352005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The impact of tobacco consumption on household catastrophic health expenditure in Türkiye.
East Mediterr Health J
December 2024
Department of Economics, Health Economics and Health Policy Research and Applciation Center, Hacettepe University, Ankara, Türkiye.
Background: Understanding the financial burden of smoking on households is crucial for developing effective strategies and policies to reduce smoking and mitigate its impact on household health.
Aim: To investigate the relationship between smoking and catastrophic health expenditure in Türkiye.
Methods: This cross-sectional study used microdata from household budget surveys conducted by the Turkish Statistical Institute in 2015 and 2019.
Summer CH ebullition strongly determines year-round greenhouse gas emissions from agricultural ditches despite frequent dredging.
J Environ Manage
December 2024
Department of Ecology, Radboud Institute for Biological and Environmental Sciences, Radboud University, Nijmegen, the Netherlands.
Recent studies indicate that greenhouse gas (GHG) emissions from agricultural drainage ditches can be significant on a per-unit area basis, but spatiotemporal investigations are still limited. Additionally, the impact of dredging - a common management in such environments - on ditch GHG emissions is largely unknown. This study presents year-round GHG emissions from nine ditches on a dairy farm in the center of the Netherlands, where each year, approximately half of the ditches are dredged in alternating cycles.
View Article and Find Full Text PDFMicrosimulation Estimates of Decision Uncertainty and Value of Information Are Biased but Consistent.
Med Decis Making
December 2024
Department of Health Policy, Stanford School of Medicine, Stanford, CA, USA.
Purpose: Individual-level state-transition microsimulations (iSTMs) have proliferated for economic evaluations in place of cohort state transition models (cSTMs). Probabilistic economic evaluations quantify decision uncertainty and value of information (VOI). Previous studies show that iSTMs provide unbiased estimates of expected incremental net monetary benefits (EINMB), but statistical properties of iSTM-produced estimates of decision uncertainty and VOI remain uncharacterized.
View Article and Find Full Text PDFBudget Impact Analysis of Implementing Patient Blood Management in the Cardiovascular Surgery Department of a Turkish Private Hospital.
Clinicoecon Outcomes Res
December 2024
Demiroğlu Bilim University, Istanbul, Turkey.
Purpose: In cardiovascular surgeries, iron deficiency anemia and transfusion of blood products are associated with mortality and morbidity, prolonged hospital stay and poor patient outcomes. Patient blood management (PBM) is a patient-centered approach based on a 'three pillar' model that promotes optimum use of blood and blood products to improve outcomes. This study assessed the potential budget impact of implementing PBM in patients undergoing elective cardiovascular surgery in a private hospital in Turkey.
View Article and Find Full Text PDFHome Visits and the Use of Routine and Emergency Postpartum Care Among Low-Income People: A Secondary Analysis of a Randomized Clinical Trial.
JAMA Netw Open
December 2024
Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Importance: Access to appropriate postpartum care is essential for improving maternal health outcomes and promoting maternal health equity.
Objective: To analyze the impact of the Nurse-Family Partnership (NFP) home visiting program on use of routine and emergency postpartum care.
Design, Setting, And Participants: This study was a secondary analysis of a randomized clinical trial that enrolled eligible participants between 2016 and 2020 to receive NFP or usual care from a South Carolina Medicaid program.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!