Severity: Warning
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Filename: drivers/Session_files_driver.php
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Filename: Session/Session.php
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Function: _error_handler
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Message: Trying to access array offset on value of type null
Filename: controllers/Detail.php
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Function: _error_handler
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Filename: controllers/Detail.php
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Function: _error_handler
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Filename: models/Detail_model.php
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Function: strpos
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Function: insertAPISummary
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Filename: helpers/my_audit_helper.php
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File: /var/www/html/application/helpers/my_audit_helper.php
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Function: str_replace
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Function: formatAIDetailSummary
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Function: _error_handler
File: /var/www/html/index.php
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Filename: controllers/Detail.php
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File: /var/www/html/application/controllers/Detail.php
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Function: _error_handler
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Background: Only a few cases have been reported about active foreign body implantation in the cavernous body of the penis.
Case Presentation: A 47-year-old man inserted two needles from the glans penis into the bilateral penile sponge body. Subsequently, two needles migrated through the penile cavernous body into the pelvic cavity. Attempts to remove the needles through the penis were unsuccessful. Eventually, after a duration exceeding one month, the displaced needles were removed in stages from the buttocks.
Conclusion: A few cases of intracavernosal-injection-therapy-associated needle breakage and retention have been reported globally. And this is the first case in China documenting the migration of foreign bodies within the penile region. In this condition, it is of utmost importance to engage the expertise of experienced andrologists to minimize the risk of excessive manipulation, thereby ensuring that inadvertent deep penetration of the needle into the penile tissue is prevented. In case the foreign body has migrated deeper into the tissues and the patient does not exhibit any specific symptoms or risks of macrovascular injury-related bleeding, close surveillance of its movement can be implemented. Surgical intervention can be initiated once the foreign body has reached a suitable position. Moreover, a psychiatric evaluation should be recommended for patient to discover any underlying mental health disorders.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11075208 | PMC |
http://dx.doi.org/10.1186/s12610-024-00224-3 | DOI Listing |
Front Surg
December 2024
Gastrointestinal Surgery Department, Baotou Central Hospital, Baotou, Inner Mongolia, China.
Introduction: The incidence of foreign bodies within the human body is uncommon, with thermometers representing an exceptionally rare subset of such cases. The management of these cases is particularly challenging due to the fragility of mercury thermometers and the toxic nature of their contents.
Case Description: A 16-year-old male adolescent presented with a three-month history of persistent, dull pain localized to the right inguinal region.
iScience
December 2024
Poltava State Medical University, Department of Pathophysiology, Poltava, Ukraine.
5-Aminolevulinic acid (5-ALA) is an essential compound in the biosynthesis of heme, playing a critical role in various physiological processes within the human body. This review provides the thorough analysis of the latest research on the molecular mechanisms and potential therapeutic benefits of 5-ALA in managing metabolic disorders. The ability of 5-ALA to influence immune response and inflammation, oxidative/nitrosative stress, antioxidant system, mitochondrial functions, as well as carbohydrate and lipid metabolism, is mediated by molecular mechanisms associated with the suppression of the transcription factor NF-κB signaling pathway, activation of the transcription factor Nrf2/heme oxygenase-1 (HO-1) system leading to the formation of heme-derived reaction products (carbon monoxide, ferrous iron, biliverdin, and bilirubin), which may contribute to HO-1-dependent cytoprotection through antioxidant and immunomodulatory effects.
View Article and Find Full Text PDFCureus
November 2024
Emergency Medicine, Memorial Healthcare System, Hollywood, USA.
Furuncular myiasis is a parasitic disease caused by the larvae of , or the human botfly, which burrow under the skin causing cystic lesions to develop. A six-year-old boy presented with multiple scalp lesions. The mother reported travel to Ecuador one month prior.
View Article and Find Full Text PDFCase Rep Dent
December 2024
Department of Dentistry, Mengo Hospital, Kampala, Uganda.
Accidental ingestion of foreign bodies during dental procedures is relatively common, with the potential for serious complications, including intestinal perforations and severe pulmonary disorders. Our case report describes the prolonged, asymptomatic retention of a swallowed hex driver in the small bowel of a 38-year-old male, managed conservatively over an extended period. The patient, with a significant medical history of depression, was undergoing a dental procedure involving implant-supported restorations when the incident occurred.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
Objective: To evaluate systemic inflammatory markers in cases of exogenous endophthalmitis caused by metal foreign bodies after penetrating eye injury and identify risk factors for poor control post-initial emergency surgery.
Methods: Twenty-nine patients with exogenous endophthalmitis underwent emergency surgery with vitrectomy at Xiamen Eye Center (2016-2024). Evaluations included systemic inflammatory markers, microbiology, clinical presentation, treatment strategies, complications, prognostic factors, and visual outcomes.
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