Demographic and clinical characteristics of our patients diagnosed with laryngeal dystonia.

Eur Arch Otorhinolaryngol

Department of Otorhinolaryngology, Pendik Training and Research Hospital, Marmara University Faculty of Medicine, Fevzi Çakmak, Muhsin Yazıcıoğlu Street, 34899, Istanbul, Turkey.

Published: August 2024

Purpose: Laryngeal dystonia (LD) is a focal dystonia affecting laryngeal musculature with no known etiology or cure. The present study evaluated the sociodemographic and clinical features of patients diagnosed with LD.

Materials And Methods: All patients diagnosed with LD at our University Hospital's Ear, Nose, and Throat Department between January 2017 and July 2023 were retrospectively analyzed. The study included 43 patients.

Results: Out of the 43 patients, 19 (44%) were male. At the time of diagnosis, the mean age of the patients was 35.1 years (ranging from 17 to 65 years). The mean elapsed time between the first symptom onset and the first diagnosis was 49.2 months (min. 4 months, max. 240 months). Of the participants, 94% had adductor-type LD. None of the patients had a family history of LD. Of the patients, 9 (20%) experienced a life-altering event or trauma just before the onset of symptoms. All patients who consumed alcohol reported symptom relief with alcohol intake. A total of 67.6% of patients stated that their symptoms were triggered by stress. All of our patients received at least one Botulinum toxin injection, with an average of 2.75 dosages per patient.

Conclusion: The gender distribution was approximately equitable between males and females. There was a tendency for men to receive a diagnosis earlier than women following the manifestation of symptoms. A significant number of patients associate the emergence of their symptoms with a stressful event or traumatic experience. This study represents the initial investigation into the sociodemographic characteristics of patients within the Turkish population.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11266236PMC
http://dx.doi.org/10.1007/s00405-024-08688-9DOI Listing

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