AI Article Synopsis
- A Delphi study has established core outcome domains (CODs) for treating adult vulvar lichen sclerosus (VLS), focusing on physical findings and quality of life (QoL).
- A systematic search identified 26 standardized measurement tools across six outcome areas, including general health, VLS-specific QoL, symptoms, clinical signs, emotional impact, and sexual functioning.
- The research highlights inconsistencies in using these measurement tools, indicating a need for a comprehensive study to create a consensus regarding evaluation methods that consider predetermined CODs and factors like age.
Article Abstract
Objectives: Core outcome domains (CODs) for treatment of adult vulvar lichen sclerosus (VLS) have recently been established through a Delphi study. A number of measuring tools are available for evaluating VLS. The aim of this study is to identify available standardized measurement tools for the major CODs for VLS that have recently been defined, namely, physical findings and quality of life (QoL) specific to VLS.
Materials And Methods: A systematic search through September 8, 2023, for measuring tools applicable to VLS regarding physical findings and QoL including sexual function or sexual well-being and self-image was performed.
Results: Thirty-five studies were included in the systematic review describing 26 tools covering the following 6 outcome domains: QoL-general health, QoL-lichen sclerosus specific, symptoms, clinical signs, emotional impact, and sexual functioning.
Conclusions: In current research, there is no uniformity in use of measurement tools for evaluating VLS. The established CODs to evaluate treatment of VLS are applicable for evaluating disease course as well. A comprehensive study to reach consensus regarding measurement of physical findings, QoL-lichen sclerosus specific, sexuality, and self-image taking the predetermined CODs and other factors such as age into account is needed.
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| http://dx.doi.org/10.1097/LGT.0000000000000819 | DOI Listing |
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