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Lower limb lymphoedema-related mental depression: A systematic review and meta-analysis of non-cancer-related studies.
Glob Epidemiol
June 2025
Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia.
Background: Lower limb lymphoedema, characterized by persistent swelling in the legs due to lymphatic dysfunction, not only imposes a physical burden but is also associated with significant mental depression. While emerging research suggests a strong link between lower limb lymphoedema and depression, the extent of the problem remains underexplored. This study aims to investigate the relationship between lower limb lymphoedema and mental depression through a meta-analysis of existing studies.
View Article and Find Full Text PDFProfiling the broad antibody diversity of lymphatic filariasis immune antibody repertoire by deep sequencing.
Int J Biol Macromol
January 2025
Institute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Penang, Malaysia; Analytical Biochemistry Research Centre, Universiti Sains Malaysia, 11800 Penang, Malaysia. Electronic address:
Lymphatic filariasis is caused by infections of thread-like filarial worms, namely Wuchereria bancrofti, Brugia Malayi and Brugia timori. However, in-depth analysis of the antibody repertoire against Lymphatic filariasis is lacking. Using high-throughput sequencing of antibody repertoires, immunome analysis of IgG (LG) and IgM (LM) repertoires were studied.
View Article and Find Full Text PDFIntegrating post-validation surveillance of lymphatic filariasis with the WHO STEPwise approach to non-communicable disease risk factor surveillance in Niue, a study protocol.
PLoS One
January 2025
Centre for Clinical Research, The University of Queensland, Brisbane, QLD, Australia.
Background: Lymphatic filariasis (LF), a mosquito-borne parasitic disease caused by three species of filarial worms, was first detected in Niue, a small Pacific Island nation of approximately 1,600 people, in 1954. After extensive efforts involving multiple rounds of Mass Drug Administration, Niue was validated by the World Health Organization (WHO) as having e4liminated LF as a public health problem in 2016. However, no surveillance has been conducted since validation to confirm infection rates have remained below WHO's elimination threshold.
View Article and Find Full Text PDFLymphangiogram of a case of presumed lymphatic filariasis with left-sided cisterna chyli.
Radiol Case Rep
March 2025
Department of Diagnostic and Interventional Radiology, Kwong Wah Hospital, Hong Kong SAR, China.
Lymphatic filariasis is an uncommon condition in Hong Kong and is currently considered as one of the neglected tropical diseases by the World Health Organization. Blood tests are available for diagnosis of acute infections, but false negative results can occur with chronic manifestations of lymphatic filariasis. We present a case which illustrates how radiological imaging can help with diagnosis of lymphatic filariasis.
View Article and Find Full Text PDFIntraspecific genetic variation in the lymphatic filariasis vector Mansonia dives (Diptera: Culicidae) in Thailand: Hidden species or genetically divergent populations?
Acta Trop
January 2025
Department of Public Health and Health Promotion, College of Allied Health Sciences, Suan Sunandha Rajabhat University, Samut Songkhram 75000, Thailand. Electronic address:
Mansonia dives is recognized as a vector for brugian filariasis in Thailand. A recent study analyzing the cytochrome c oxidase subunit I (COI) gene revealed two distinct clades within the Ma. dives population in Thailand.
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