AI Article Synopsis
- - Pneumatosis intestinalis (PI) is the presence of air in the bowel wall, which can be caused by various factors, including chemotherapy treatments like 5-fluorouracil (5-FU).
- - A case study details a 70-year-old male with metastatic tongue squamous cell carcinoma who developed PI during treatment, linked to 5-FU, despite having reassuring diagnostic findings.
- - The patient was treated conservatively with antibiotics and bowel rest, leading to stable imaging results and a successful discharge without complications, emphasizing the need to recognize 5-FU as a potential cause of PI and the effectiveness of conservative management.
Article Abstract
Pneumatosis intestinalis (PI) refers to the presence of air within the bowel wall. It can be associated with many causes including chemotherapy. We report a case of a 70-year-old male with metastatic tongue squamous cell carcinoma (SCC), whose hospital course was complicated by diarrhea and the development of PI, which was attributed to 5-fluorouracil (5-FU) chemotherapy after a comprehensive diagnostic workup and reassuring physical examination. The patient was treated conservatively with antibiotics and a bowel rest. A repeat imaging done before discharge showed stable findings. The patient was discharged afterward without complications. We highlight the importance of recognizing 5-FU as a cause for PI among patients with reassuring physical examination and diagnostic workup. Furthermore, we highlight that it may still be successfully managed with conservative measures.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11069635 | PMC |
| http://dx.doi.org/10.7759/cureus.57576 | DOI Listing |
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