Pediatric craniomaxillofacial reconstruction must be approached through the lens of growth and durability. A systematic approach of matching defects to donor tissue drives the selection of autologous reconstructive technique. The menu of available methods for reconstruction can be organized in a manner similar to adults, with special considerations for growth and development. Reconstructive surgeons have the opprtunity to promote and maintain young patients' sense of identity during psychosocial development.
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Phase I-IIa clinical trial to evaluate the safety, feasibility and efficacy of the use of a palate mucosa generated by tissue engineering for the treatment of children with cleft palate: the BIOCLEFT study protocol.
BMJ Open
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Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain
Introduction: The current gold standard treatment for patients with orofacial clefts is surgical repair of the palatal defect (uranostaphylorrhaphy), which is associated with growth defects and hypoplasia of the maxillofacial structures. This trial aims to evaluate the potential of a bioengineered artificial palate mucosa, created through tissue engineering with autologous stromal and epithelial cells and nanostructured fibrin-agarose biomaterials, to enhance treatment outcomes for patients with unilateral cleft lip and palate.
Methods And Analysis: This phase I-IIa clinical trial aims to evaluate the feasibility and biosafety of a procedure involving grafting bioartificial palate mucosa onto the areas of denudated bone in patients undergoing uranostaphylorrhaphy.
Impact of Cleft and Craniofacial Surgery Experience in Oral and Maxillofacial Surgery Residency Training Programs.
J Oral Maxillofac Surg
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Professor in Oral and Maxillofacial Surgery and Pediatrics, Department of Surgery, Emory University School of Medicine, Chief of Oral and Maxillofacial Surgery, Children's Healthcare of Atlanta, Atlanta, GA.
Background: The impact of cleft and craniomaxillofacial (CCMF) surgeons on oral and maxillofacial surgery (OMS) resident training is not well known.
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Management of paediatric sialorrhea.
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Department of Neurodevelopment and Disability, The Royal Children's Hospital, Parkville Department of Pediatrics, The University of Melbourne, Murdoch Children's Research Institute, Melbourne, Australia.
Purpose Of Review: To summarize current understanding of and recent literature on the management of sialorrhea in children.
Recent Findings: Sialorrhea is a symptom of oropharyngeal dysphagia and reduced clearance. Sialorrhea can be anterior, with forward overflow of saliva, causing skin rash, social embarrassment and spillage on communication devices; or posterior, where there is pharyngeal pooling of saliva, which may cause aspiration.
Smartphone-based scans of palate models of newborns with cleft lip and palate: Outlooks for three-dimensional image capturing and machine learning plate tool.
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Department of Periodontology, School of Dentistry, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Article Synopsis
- - The study aimed to assess how well smartphone scanning apps could create 3D models of different types of cleft palate and to test a machine learning tool for generating presurgical plates (PSP).
- - Two apps were evaluated on 15 cleft palate models and scans were conducted both with and without a mirror, comparing results to professional intraoral scanner outputs.
- - Findings indicated KIRI performed best for unilateral cleft models without a mirror, while a machine learning tool effectively predicted landmarks for PSP creation, although it struggled with isolated cleft palates.
Mandibular response after rapid maxillary expansion in mixed dentition children with different vertical growth patterns: a retrospective study.
J Clin Pediatr Dent
September 2024
Department of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, 200001 Shanghai, China.
This study evaluated the mandibular development induced by rapid maxillary expansion (RME) therapy in mixed dentition patients with different vertical growth patterns through long-term observation. The research utilized a retrospective design that included two cohorts: a control group consisting of pediatric subjects with individualized malocclusions, and an experimental group received RME therapy. A total of 60 subjects were included; 37 in the RME group (17 males and 20 females) and 23 in the control group (13 males and 10 females).
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