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Binding a stimulus after, but not before, response execution: examining the temporal binding window of event files.
Psychol Res
January 2025
University of Toronto, Toronto, Canada.
Efficient and flexible responses are essential for successfully interacting with the environment. These interactions require an instantaneous integration of visual stimuli and responses, known as 'stimulus-response binding' (SR binding). SR binding is considered part of a holistic temporary representation, the event file, that integrates the stimulus, the response, and the action effect produced by this response.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
University of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA.
Background: Plasma biomarkers show a promising future to improving the quality of diagnosing Alzheimer's Disease (AD). However, blood processing procedures should be considered when measuring plasma biomarkers. Here we investigate brain-derived neurotrophic factor (BDNF) in platelet-rich and platelet-poor plasma.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Beijing Key Laboratory of Geriatric Cognitive Disorders, Beijing, China.
Background: Hippocampal atrophy is being characterized as a key biomarker in neurodegenerative disease, especially for dementia. Nevertheless, detecting hippocampus relied on magnetic resonance imaging (MRI), it's very costly and time-consuming. Our objective is to develop a predictive score to detect MRI-related hippocampal volume based on large-scale blood proteomics.
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Alzheimers Dement
December 2024
Medical University of South Carolina, Charleston, SC, USA.
Background: Alzheimer's Disease and related dementias (ADRD) are a critical healthcare crisis in the State of South Carolina (SC), with over 115,000 individuals diagnosed with ADRD accounting for 11% of South Carolinians aged 65 or over and 52% of South Carolinians aged 85 or over. Exorbitant resources are used to care for these individuals, including $650 million in Medicaid dollars and over 300 million hours of unpaid caregiver time. SC has enacted a statewide plan to address ADRD with the mission of promoting "a comprehensive approach to risk reduction, early detection and diagnosis, high-quality dementia services, and a coordinated and equitable continuum of care across…" Yet, ADRD does not present uniformly across SC.
View Article and Find Full Text PDFBackground: Building a foundation of trust is the first step to establishing a relationship with the community that transcends any enrollment period. The Memory and Aging Program (MAP) Outreach Team formed in 2016 and has grown to a core of four team members in 2022, all focused on educating the public about Alzheimer's Disease and Related Disorders (ADRD) and sharing opportunities to participate in research. This team explores different approaches to improve the access underrepresented populations (URPs) have to research and share some of their takeaways from community events.
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