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Meta-analysis of MitraClip and PASCAL for transcatheter mitral edge-to-edge repair.
J Cardiothorac Surg
January 2025
Department of Internal Medicine II, Städtisches Klinikum Solingen, Solingen, Germany.
Article Synopsis
- The study compares the safety and efficacy of the MitraClip and PASCAL systems for treating mitral regurgitation (MR), finding limited differences.
- A total of eight studies involving 1,612 patients were analyzed, showing no significant variation in MR severity reduction between the two devices.
- Both devices demonstrated similar safety and procedural success, though PASCAL showed a slight trend toward better MR reduction, but without statistically significant results.
Outcomes and Impact of Device Iterations in Mitral Valve Transcatheter Edge-to-Edge Repair: The REPAIR Study.
JACC Cardiovasc Interv
November 2024
Department of Cardiology, Heart Center, Faculty of Medicine, University of Cologne, Cologne, Germany. Electronic address:
Background: The PASCAL P10 system for mitral valve transcatheter edge-to-edge repair has undergone iterations, including introduction of the narrower Ace implant and the Precision delivery system.
Objectives: The study sought to evaluate outcomes and the impact of PASCAL mitral valve transcatheter edge-to-edge repair device iterations.
Methods: The REPAIR (REgistry of PAscal for mltral Regurgitation) study is an investigator-initiated, multicenter registry including consecutive patients with mitral regurgitation (MR) treated from 2019 to 2024.
The Impact of Postprocedural Anticoagulant Use in Patients Undergoing Woven EndoBridge: A Multicenter Propensity Score-Matched Study.
Transl Stroke Res
December 2024
Department of Neurological Surgery, Thomas Jefferson University Hospital, 901 Walnut street 3rd Floor, Philadelphia, PA, 19107, USA.
The Woven EndoBridge (WEB) device has become a prominent treatment for wide-neck bifurcation intracranial aneurysms since its FDA approval in 2018. However, the impact of anticoagulant therapy on its efficacy and patient outcomes remains underexplored. This study aims to evaluate the effects of postoperative anticoagulant use on aneurysm occlusion, retreatment rates, and functional outcomes following WEB device implantation.
View Article and Find Full Text PDFUnavoidable Iatrogenic Mitral Stenosis Following Transcatheter Edge-to-Edge Mitral Valve Repair With Current Devices.
JACC Cardiovasc Interv
November 2024
Department of Cardiology Center, Sendai Kousei Hospital, Sendai, Miyagi, Japan.
Association of aortic root diameter and vascular function with an exaggerated blood pressure response to exercise among elite athletes.
Clin Res Cardiol
December 2024
Department of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Background: The systolic blood pressure/workload (SBP/MET) slope was recently reported to reliably identify an exaggerated blood pressure response (eBPR) in the normal population and in athletes. We investigated whether the aortic root diameter (AoD) also correlates with an eBPR and vascular function in elite athletes.
Methods: We examined 652 healthy male elite athletes (age 25.
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