AI Article Synopsis
- Plant-derived extracellular vesicles (PDEV) are tiny structures made of lipids, proteins, and nucleic acids that help in transferring substances and information between plant cells and different species.
- Recent research shows that PDEV is safe, stable, and easy to source, making it useful for treating various diseases, particularly in musculoskeletal disorders.
- The article discusses the characteristics and isolation methods of PDEV, as well as its potential as a drug delivery system, highlighting its significance in medical applications.
Article Abstract
Plant-derived extracellular vesicles (PDEV) constitute nanoscale entities comprising lipids, proteins, nucleic acids and various components enveloped by the lipid bilayers of plant cells. These vesicles play a crucial role in facilitating substance and information transfer not only between plant cells but also across different species. Owing to its safety, stability, and the abundance of raw materials, this substance has found extensive utilization in recent years within research endeavors aimed at treating various diseases. This article provides an overview of the pathways and biological characteristics of PDEV, along with the prevalent methods employed for its isolation, purification, and storage. Furthermore, we comprehensively outline the therapeutic implications of diverse sources of PDEV in musculoskeletal system disorders. Additionally, we explore the utilization of PDEV as platforms for engineering drug carriers, aiming to delve deeper into the significance and potential contributions of PDEV in the realm of the musculoskeletal system.
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| http://dx.doi.org/10.1016/j.phrs.2024.107202 | DOI Listing |
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