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Probiotics interventions modulating gut microbiota composition in individuals with intestinal constipation: Protocol of a systemic review and meta-analysis of randomized controlled trials.
PLoS One
January 2025
Department of Anorectal Surgery, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Introduction: Intestinal constipation is a substantive global health concern, significantly impairing patient quality of life. An emerging view is that the gut microbiota plays a critical role in intestinal function, and probiotics could offer therapeutic benefits. This study aims to consolidate evidence from randomized controlled trials (RCTs) that assess the effectiveness of probiotics in modulating microbiota and ameliorating symptoms of constipation.
View Article and Find Full Text PDFOrganoid Ethical Typology: varieties of three-dimensional stem cell constructs and the many issues they raise in bioethics.
Biol Cell
January 2025
Institut supérieur de philosophie, UCLouvain, Louvain-la-Neuve, Belgium.
The advancement of and prospects for stem cell research raise a number of specific ethical issues. While navigating the ethical landscape of stem cell research is often challenging for biology researchers and biotechnology innovators, it is also difficult for the public and other persons of concern (from ethicists to policy-makers) to grasp the technicalities of a burgeoning field that develops in many directions. Organoids are one of these new biotechnological constructs that are currently eliciting a rich debate in bioethics.
View Article and Find Full Text PDFAging Concerns Related to Sexuality and Gender: HIV Prevention and Healthy Aging.
AIDS Behav
January 2025
Department of Human Development and Family Sciences, University of Connecticut, Storrs, CT, USA.
Healthy aging is an important area of research across many populations, but less work has focused on this area among sexual and gender diverse individuals relative to the general population. On the whole, it is known that as the U.S.
View Article and Find Full Text PDFDistribution of pharmaceuticals in marine surface sediment and macroalgae (ulvophyceae) around Mombasa peri-urban creeks and Gazi Bay, Kenya.
Environ Sci Pollut Res Int
January 2025
Department of Chemistry, University of Pretoria, Hatfield, Pretoria, South Africa.
Pollution in marine creeks has been increasing due to anthropogenic activities and has been a global concern. Limited research has been conducted on pharmaceuticals in marine sediment and macroalgae in African countries. In the present study, the levels of pharmaceuticals were assessed in surface sediment and different species of macroalgae (ulvophyceae; Cladophora sudanensis, Chaetomorpha crassa, Chaetomorpha indica, Enteromorpha kylinii, Ulva reticulate, Ulva lactuca and Cladophora sibugae) in Mombasa peri-urban creeks (Tudor, Makupa and Mtwapa creek) and Gazi bay during dry and wet seasons.
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