Social ties, either positive or negative, lead to signed network patterns, the subject of balance theory. For example, strong balance introduces cycles with even numbers of negative edges. The statistical significance of such patterns is routinely assessed by comparisons to null models. Yet, results in signed networks remain controversial. Here, we show that even if a network exhibits strong balance by construction, current null models can fail to identify it. Our results indicate that matching the signed degree preferences of the nodes is a critical step and so is the preservation of network topology in the null model. As a solution, we propose the STP null model, which integrates both constraints within a maximum entropy framework. STP randomization leads to qualitatively different results, with most social networks consistently demonstrating strong balance in three- and four-node patterns. On the basis our results, we present a potential wiring mechanism behind the observed signed patterns and outline further applications of STP randomization.
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http://dx.doi.org/10.1126/sciadv.adj0104 | DOI Listing |
Phys Chem Chem Phys
January 2025
Department of Physics, Assam University, Silchar-788011, India.
Density functional theory has been employed to study indolo[3,2,1-]carbazole donor-based dyes, incorporating one and two units of 2,4-dimethoxybenzene auxiliary donors. Electrostatic potential analysis highlights the dye with one auxiliary donor (D2) as having the highest charge-donating capability. Structural analysis shows that auxiliary donors enhance planarity, reduce steric hindrance, and improve π-conjugation.
View Article and Find Full Text PDFWearable Technol
November 2024
Department of Kinesiology, Iowa State University, Ames, IA, USA.
Placing an inertial measurement unit (IMU) at the 5th lumbar vertebra (L5) is a frequently employed method to assess the whole-body center of mass (CoM) motion during walking. However, such a fixed position approach does not account for instantaneous changes in body segment positions that change the CoM. Therefore, this study aimed to assess the congruence between CoM accelerations obtained from these two methods.
View Article and Find Full Text PDFJ Neural Eng
January 2025
Institute of Semiconductors Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing, 100083, CHINA.
Objective: Steady-state visual evoked potentials (SSVEPs) rely on the photic driving response to encode electroencephalogram (EEG) signals stably and efficiently. However, the user experience of the traditional stimulation with high-contrast flickers urgently needs to be improved. In this study, we introduce a novel paradigm of grid stimulation with weak flickering perception, distinguished by a markedly lower proportion of stimulation area in the overall pattern.
View Article and Find Full Text PDFRen Fail
December 2025
Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Identifying risk factors for disease onset and progression has been a core focus in nephrology research. Mendelian Randomization (MR) has emerged as a powerful genetic epidemiological approach, utilizing genome-wide association studies (GWAS) to establish causal relationships between modifiable risk factors and kidney disease outcomes. MR uses genetic variants as instrumental variables to infer causal relationships between exposures and disease outcomes.
View Article and Find Full Text PDFSupport Care Cancer
January 2025
Department of Inner Medicine II (Hematology/Oncology) and University Cancer Center, Schleswig-Holstein (UCCSH), University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.
Background: Prior research indicates that engaging in physical activity during chemotherapy can positively influence both physical and psychological parameters in individuals with hematological neoplasms. However, the most effective type, level, intensity, and frequency of exercise remains unclear.
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