AI Article Synopsis

  • - This study investigated the link between small fish consumption and mortality rates, focusing on a cohort of 80,802 participants in Japan aged 35-69.
  • - Results showed that higher intake of small fish significantly lowered the risk of all-cause and cancer-related deaths in females, while no notable relationship was found for males.
  • - The findings suggest that incorporating small fish into the diet may be beneficial for reducing mortality risks, particularly for women.

Article Abstract

Objective: Although small fish are an important source of micronutrients, the relationship between their intake and mortality remains unclear. This study aimed to clarify the association between intake of small fish and all-cause and cause-specific mortality.

Design: We used the data from a cohort study in Japan. The frequency of the intake of small fish was assessed using a validated FFQ. The hazard ratio (HR) and 95 % confidence interval (CI) for all-cause and cause-specific mortality according to the frequency of the intake of small fish by sex were estimated using a Cox proportional hazard model with adjustments for covariates.

Setting: The Japan Multi-Institutional Collaborative Cohort Study.

Participants: A total of 80 802 participants (34 555 males and 46 247 females), aged 35-69 years.

Results: During a mean follow-up of 9·0 years, we identified 2482 deaths including 1495 cancer-related deaths. The intake of small fish was statistically significantly and inversely associated with the risk of all-cause and cancer mortality in females. The multivariable-adjusted HR (95 % CI) in females for all-cause mortality according to the intake were 0·68 (0·55, 0·85) for intakes 1-3 times/month, 0·72 (0·57, 0·90) for 1-2 times/week and 0·69 (0·54, 0·88) for ≥ 3 times/week, compared with the rare intake. The corresponding HR (95 % CI) in females for cancer mortality were 0·72 (0·54, 0·96), 0·71 (0·53, 0·96) and 0·64 (0·46, 0·89), respectively. No statistically significant association was observed in males.

Conclusions: Intake of small fish may reduce the risk of all-cause and cancer mortality in Japanese females.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11148834PMC
http://dx.doi.org/10.1017/S1368980024000831DOI Listing

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