AI Article Synopsis
- Preventive chemotherapy through mass drug administration is recommended to eliminate schistosomiasis, particularly in at-risk children in sub-Saharan Africa.
- A systematic review analyzed 3455 studies to evaluate the effectiveness of paediatric schistosomiasis control programs, resulting in 30 relevant studies being included.
- The findings indicate that while preventive chemotherapy reduces schistosomiasis prevalence, high rates of re-infection remain, emphasizing the need for additional interventions like safe water access, sanitation, and health education to achieve effective elimination.
Article Abstract
Preventive chemotherapy by mass drug administration is globally recommended as the primary method of reaching the elimination of schistosomiasis, especially in the high risk-paediatric population. This systematic review provides a summary of the effects of paediatric schistosomiasis control programs on eliminating schistosomiasis in sub-Saharan Africa. A systematic search was conducted in PubMed, EBSCOhost, and other databases to obtain studies regarding the effects of paediatric schistosomiasis control programmes in sub-Saharan Africa. 3455 studies were screened for eligibility, included articles reported on both paediatrics control programmes and schistosomiasis, and articles were excluded when they did not report on schistosomiasis control programmes in paediatrics exclusively. 40 selected studies were critically appraised using the JBI critical appraisal tools for relevance and 30 studies were included in the study. An in-depth quantitative descriptive analysis was conducted, and a comprehensive narrative summary explained the results within the scope of the review questions. The results show that despite preventive chemotherapy lowering schistosomiasis prevalence, chances of re-infection are high in endemic areas. Preventive chemotherapy without complementary interventions including safe water provision and proper sanitation, snail control and health education on the aetiology of schistosomiasis, transmission pattern and control practices might not eliminate schistosomiasis.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11065241 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0301464 | PLOS |
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