A radical ring-opening arylation of cyclopropanol with 1,2,3-triazole has been achieved. This synthetic protocol provides straightforward access to a wide range of structurally diverse and chiral 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-]pyridines with high efficiency from readily available chiral cyclopropanols.
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| http://dx.doi.org/10.1021/acs.orglett.4c00702 | DOI Listing |
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