The synthesis of amines through -alkylation is particularly attractive. Herein, a strategy for visible-light-induced -alkylation of anilines with 4-hydroxybutan-2-one was developed in the presence of NHBr, which avoid the use of metals, bases and ligands. In addition, gram-scale experiments proved that the system has the potential to be scaled.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11061780 | PMC |
| http://dx.doi.org/10.1039/d4ra01339e | DOI Listing |
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