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Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease. | LitMetric
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Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease.

Akshay Sharma Subodh Selukar Yu Bi Anthony Merlocco Cara E Morin Chris Goode Parul Rai Jeffrey A Towbin Jane S Hankins Stephen Gottschalk Brandon Triplett Jason N Johnson

Blood

Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN.

Published: August 2024

Serial cardiovascular magnetic resonance evaluation of children and young adults with SCD who underwent hematopoietic cell transplantation showed mean ECV, representing diffuse myocardial fibrosis, decreased 3.4% from baseline to 12 months posttransplantation. This trial was registered at www.clinicaltrials.gov as #NCT04362293.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347799PMC
http://dx.doi.org/10.1182/blood.2023023028DOI Listing

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