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Risk of major vascular events in patients without traditional risk factors after transient ischemic attack or minor ischemic stroke: An international prospective cohort.
Eur Stroke J
November 2024
Department of Neurology and Stroke Center, Bichat Hospital, Paris, France.
Article Synopsis
- - The study analyzed 3847 patients who suffered from a transient ischemic attack or minor ischemic stroke, focusing on those without traditional risk factors (like hypertension and diabetes) to compare their outcomes with those who did have risk factors.
- - After one year, the risk of major cardiovascular events (MACE) was similar between the two groups, but after five years, those without traditional risk factors had a significantly lower risk of MACE (7.9% vs 13.9%).
- - In patients without traditional risk factors, arterial stenosis was identified as a critical predictor for MACE, indicating that while their long-term risk was lower, they were not entirely without risk.
Optic disc pit maculopathy: Covering or filling technique with human amniotic membrane patch to treat the optic disc pit maculopathy?
Eur J Ophthalmol
November 2024
Eye Clinic, Department of Experimental and Clinical Medicine, Polytechnic University of Marche, Ancona, Italy.
Purpose: To describe two patients affected by optic disk pit-maculopathy ODP-M surgically treated with pars-plana vitrectomy (PPV) and the apposition of a human Amniotic Membrane (hAM) patch.
Methods: Patients underwent a PPV with the apposition of a hAM patch to cover the ODP. In case 1, a 2 surgery was necessary to push the hAM patch inside the pit, whereas in case 2 the patch was pulled inside the pit following the pressure gradient when infusion was turned on.
Neuronal tissue collection from intra-cranial instruments used in deep brain stimulation surgery for Parkinson's disease with implications for study of alpha-synuclein.
Sci Rep
September 2024
University of Florida College of Medicine, 1505 SW Archer Rd, Gainesville, FL, 32608, USA.
Alpha-synuclein (αSyn) forms pathologic aggregates in Parkinson's disease (PD) and is implicated in mechanisms underlying neurodegeneration. While pathologic αSyn has been extensively studied, there is currently no method to evaluate αSyn within the brains of living patients. Patients with PD are often treated with deep brain stimulation (DBS) surgery in which surgical instruments are in direct contact with neuronal tissue; herein, we describe a method by which tissue is collected from DBS surgical instruments in PD and essential tremor (ET) patients and demonstrate that αSyn is detected.
View Article and Find Full Text PDFMultiple primary diffuse large B-cell lymphoma masquerading as meningioma.
Surg Neurol Int
July 2024
Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
Article Synopsis
- Primary non-Hodgkin's lymphoma, specifically diffuse large B-cell lymphoma (DLBCL), can present as mass lesions similar to meningioma in immunocompetent patients, making diagnosis difficult.
- A case of a young female with DLBCL showed involvement of the scalp and brain, initially resembling a meningioma, and despite surgical intervention, she developed systemic disease two months post-surgery.
- Proper diagnosis typically requires histological examination after tumor resection, and early initiation of chemotherapy is crucial for managing this rare condition.
An algorithm for the surgical approach to spontaneous temporal bone CSF leak.
Am J Otolaryngol
August 2024
Department of Otolaryngology Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel; Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address:
Objective: To suggest a comprehensive algorithm for the surgical approach for correcting of sources of temporal bone CSF leaks.
Methods: A case series for patients operated in a single academic tertiary referral center between 2011 and 4.2022.
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