Despite the clinical success of tricalcium silicate (TCS)-based materials in endodontics, the inferior handling characteristic, poor anti-washout property and slow setting kinetics hindered their wider applications. To solve these problems, an injectable fast-setting TCS/β-tricalcium phosphate/monocalcium phosphate anhydrous (β-TCP/MCPA) cement was developed for the first time by incorporation of hydroxypropyl methylcellulose (HPMC) and β-TCP/MCPA. The physical-chemical characterization (setting time, anti-washout property, injectability, compressive strength, apatite mineralization and sealing property) of TCS/(β-TCP/MCPA) were conducted. Its hydration mechanism was also investigated. Furthermore, the cytocompatibility and osteogenic/odontogenic differentiation of stem cells isolated from human exfoliated deciduous teeth (SHED) treated with TCS/β-TCP/MCPA were studied. The results showed that HPMC could provide TCS with good anti-washout ability and injectability but slow hydration process. However, β-TCP/MCPA effectively enhanced anti-washout characteristics and reduced setting time due to faster hydration kinetics. TCS/(β-TCP/MCPA) obtained around 90 % of injection rate and high compressive strength whereas excessive additions of β-TCP/MCPA compromised its injectability and compressive strength. TCS/(β-TCP/MCPA) can induce apatite deposition and form a tight marginal sealing at the dentin-cement interface. Additionally, TCS/(β-TCP/MCPA) showed good biocompatibility and promoted osteo/odontogenic differentiation of SHED. In general, our results indicated that TCS/(β-TCP/MCPA) may be particularly promising as an injectable bioactive cements for endodontic treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijbiomac.2024.131580 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Role of calcination process of natural colemanite powder on compressive strength property of concrete.
Heliyon
January 2025
Department of Civil Engineering, Faculty of Engineering and Architecture, Recep Tayyip Erdogan University, 53100, Rize, Turkey.
The use of boron minerals as an additive is important in terms of reducing CO emissions and providing input to the economy. Sustainable natural colemanite was subjected to calcination at 550 °C in order to concentrate the amount of BO. For the characterization of calcined mineral, XRD, TGA/DTA, and BO component tests were carried out.
View Article and Find Full Text PDFHierarchical Biogenic-Based Thermal Insulation Foam.
ACS Nano
January 2025
Department of Materials Science and Engineering, University of Maryland, College Park, Maryland 20742, United States.
Biogenic-based foam, renowned for its sustainable and eco-friendly properties, is emerging as a promising thermal insulating material with the potential to significantly enhance energy efficiency and sustainability in building applications. However, its relatively high thermal conductivity, large-pore configurations, and energy-intensive manufacturing processes hinder its widespread use. Here, we report on the scalable, one-pot synthesis of biogenic foams achieved by integrating recycled paper pulp and in situ nanoporous silica formation, resulting in a hierarchical structure comprising both micropores and nanopores.
View Article and Find Full Text PDFTemperature dynamics and mechanical properties analysis of carbon fiber epoxy composites radiated by nuclear explosion simulated light source.
Sci Rep
January 2025
Engineering Research Center of Flexible Radiation Protection Technology, Universities of Shaanxi Province, Xi'an Polytechnic University, Xi'an, 710048, Shaanxi, China.
The impact of light radiation, a predominant energy release mechanism in nuclear explosions, on material properties is of critical importance. This investigation employed an artificial light source to replicate the effects of nuclear explosion radiation and utilized a physical information neural network (PINN) to examine the temperature evolution and corresponding changes in the mechanical properties of carbon fiber/epoxy composites (CFEC). A light source simulating nuclear explosion's light radiation was built to irradiate the CFEC, then measure the reflection spectrum and temperature of samples.
View Article and Find Full Text PDFInvestigating slope stability of multiple stopes prone to instability in the Ziluoyi iron ore mining site.
Sci Rep
January 2025
School of Safety Engineering, China University of Mining and Technology, Xuzhou, 221116, China.
The ore mining sites commonly experience slope instability, which is causing concern for the workers' safety and the operation's stability. Considering the Ziluoyi iron ore mining site as a case study, uniaxial compression strength and shear tests are performed on the lower disk peripheral rock, ore body, and upper disk peripheral rock, leading to the extraction of compressive strength and elastic modulus (lower disk: 77.7 MPa-9.
View Article and Find Full Text PDFDamage constitutive model and mechanical properties of a concrete limestone composite after acid corrosion.
Sci Rep
January 2025
College of Civil Engineering, Guizhou University, Huaxi District, Guiyang, 550025, Guizhou, China.
Long-term erosion by acidic solutions in karst regions leads to continuous deterioration of the physical and mechanical properties at the interfaces of engineering structures, adversely affecting their operational performance. To investigate the degradation patterns of the mechanical properties and corrosion mechanisms of the concrete‒limestone composite (CLC) after exposure to acidic corrosion, three kinds of CLC samples treated with acidic solutions of different pH values were fabricated. Mechanical property analysis was conducted via triaxial compression testing methods.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!