Treatment of temporomandibular ankylosis complicating masseter muscle cellulitis in three patients, as a result of a dental lesion, required wide excision of bone structure and, in two cases, of adjacent infected soft tissues.

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Objective: This study aimed to assess the prevalence of temporomandibular dysfunction in ankylosing spondylitis patients and healthy controls, examining the relationship between temporomandibular dysfunction and disease activity in ankylosing spondylitis patients, as well as associations with psychosocial factors.

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Causal Relationship Between Autoimmune Arthritis and Temporomandibular Disorders.

Int Dent J

September 2024

Department of Stomatology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China; Hubei Key Laboratory of Embryonic Stem Cell Research, Hubei Provincial Clinical Research Center for Umbilical Cord Blood Hematopoietic Stem Cells, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, China. Electronic address:

Article Synopsis
  • - The study investigated the causal relationship between autoimmune arthritis (AA) and temporomandibular disorders (TMD) using a method called bidirectional Mendelian randomization analysis.
  • - Researchers analyzed data from the FinnGen and IEU databases and found that certain types of AA, specifically rheumatoid arthritis (RA) and ankylosing spondylitis (AS), may significantly increase the risk of developing TMD.
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Background: The role of autoimmune diseases (ADs) in temporomandibular disorders (TMDs) has been emphasized in observational studies. However, whether the causation exists is unclear, and controversy remains about which specific disorder is destructive in TMDs. This Mendelian randomization (MR) study aims to estimate the causal effect of common ADs on TMDs.

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