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Tongue Muscle Training App for Middle-Aged and Older Adults Incorporating Flow-Based Gameplay: Design and Feasibility Pilot Study.
JMIR Serious Games
January 2025
Department of Interaction Design, National Taipei University of Technology, Rm.701-4, Design Building, No.1, Sec.3, Chung-hsiao E. Rd, Taipei, 10608, Taiwan, 886 912-595408, 886 2-87732913.
Background: Complications due to dysphagia are increasingly prevalent among older adults; however, the tediousness and complexity of conventional tongue rehabilitation treatments affect their willingness to rehabilitate. It is unclear whether integrating gameplay into a tongue training app is a feasible approach to rehabilitation.
Objective: Tongue training has been proven helpful for dysphagia treatment.
Facilitating multidisciplinary working groups in translational research: Strategies to promote cross-center collaboration and sustain the Cancer Center Cessation Initiative Consortium.
J Clin Transl Sci
November 2024
Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA.
As funding for large translational research consortia increases across the National Institutes of Health (NIH), focused working groups provide an opportunity to leverage the power of unique networks to conduct high-impact science and offer a strategy for building collaborative infrastructure to sustain networks long-term. This sustainment leverages the existing NIH investments, amplifying the impact and creating conditions for future innovative translational research. However, few resources exist that detail practical strategies for establishing and sustaining working groups in consortia.
View Article and Find Full Text PDFRisk of infections in bispecific antibody therapy for multiple myeloma: a comprehensive review of literature.
Hematology
December 2025
Clinical Pharmacy Department, King Fahad Medical City, Riyadh, RH, Saudi Arabia.
Multiple Myeloma (MM) is a malignancy characterized by abnormal production of monoclonal immunoglobulins in plasma cells. Bispecific antibodies have emerged as a significant advancement in MM treatment, offering high effectiveness and specificity by targeting different antigens such as BCMA, CD38, and FcRH5. However, the risk of infection poses a major challenge in MM patients, which is thought to be influenced by various factors.
View Article and Find Full Text PDFAssessing the impacts of stakeholder involvement in long-term agricultural experiments via a case study in the upper US Midwest.
J Environ Qual
January 2025
W.K. Kellogg Biological Station, Michigan State University, Hickory Corners, Michigan, USA.
Agricultural researchers are increasingly encouraged to engage with stakeholders to improve the usefulness of their projects, but iterative research on the design and assessment of stakeholder engagement is scarce. The USDA Long-Term Agroecosystem Research (LTAR) Network recognizes the importance of effective engagement in increasing the utility of information and technologies for future agriculture. Diverse stakeholders and researchers at the Kellogg Biological Station (KBS) LTAR site co-designed the KBS LTAR Aspirational Cropping System Experiment, a process that provides a testing ground and interdisciplinary collaborations to develop theory-driven assessment protocols for continuous stakeholder engagement.
View Article and Find Full Text PDFAsymptomatic infection and antibody prevalence to co-occurring avian influenza viruses vary substantially between sympatric seabird species following H5N1 outbreaks.
Sci Rep
January 2025
Institute of Ecology and Evolution, School of Biological Sciences, University of Edinburgh, Ashworth Laboratories, King's Buildings, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK.
Emerging infectious diseases are of major concern to animal and human health. Recent emergence of high pathogenicity avian influenza virus (HPAIV) (H5N1 clade 2.3.
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