AI Article Synopsis
- The study aimed to investigate the characteristics of community-acquired pneumonia (CAP) in patients also suffering from type 2 diabetes (T2D) to help with early diagnosis and treatment.
- A total of 93 patients were analyzed using metagenomics next-generation sequencing, with 46 having CAP/T2D and 47 without diabetes, revealing significant differences in various health metrics between the two groups.
- Results indicated that patients with CAP/T2D had higher infection rates and levels of inflammation markers, while their albumin levels were lower compared to those without diabetes, suggesting a more severe condition in the case group.
Article Abstract
Objective: To study the etiological characteristics of community-acquired pneumonia (CAP) combined with type 2 diabetes (T2D), providing a reference for early clinical diagnosis and treatment of the disease.
Methods: We selected a total of 93 patients with CAP and analyzed their metagenomics nextgeneration sequencing (mNGS) data. The case group comprised 46 patients with combined CAP/T2D, and the control group comprised 47 patients without diabetes. We analyzed the pathogenic findings of the two groups.
Results: There were statistically significant differences in age between the two groups (P = 0.001). Leukocytes (P = 0.012), blood platelets (P = 0.034), fibrinogen (P = 0.037), D-dimer (P = 0.000), calcitonin ogen (P = 0.015), ultrasensitive C-reactive protein or C-reactive protein (CRP) (P = 0.000), serum amyloid A (P = 0.000), and erythrocyte sedimentation rate (P = 0.003) were higher in the case group than in the control group. Albumin was lower in the case group than in the control group. All differences were statistically significant. The infection rates of (P = 0.030), (P = 0.043), and (P = 0.032) were significantly different between the two groups.
Conclusion: Compared with those without diabetes, the infection rates of were higher in patients with combined CAP/T2D.
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| http://dx.doi.org/10.2174/0118715303273741231117060753 | DOI Listing |
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