AI Article Synopsis
- Acrochordons, or skin tags, are common and benign skin growths; this study investigates their association with obesity and metabolic syndrome in children, an area that has been largely unexplored compared to adults.
- The study analyzed outpatient dermatology patients from 2000 to 2021, focusing on children under 18 diagnosed with acrochordons, and collected various health data to evaluate their body mass index (BMI) and the presence of metabolic syndrome.
- Findings revealed that nearly half of the children in the study were classified as obese, with a higher prevalence of obesity and related health conditions compared to a general US population sample, suggesting acrochordons may indicate metabolic health issues in kids.
Article Abstract
Background: Acrochordons or skin tags are common benign skin growths. Several studies explored the relationship between obesity and metabolic syndrome in adults but remains unexplored in children.
Methods: This was a single-center retrospective cohort study of outpatient dermatology patients between 1 January 2000 to 1 January 2021. Children under 18 years old diagnosed with acrochordons using diagnostic codes International Classification of Diseases, 10th Revision (ICD-10) L91.8 and 9th Revision (ICD-9) 701.8 were included. We collected patient demographics, past medical history, laboratory values, vital signs, and physical exam. Body mass index (BMI) was calculated and stratified into categories based on the Center for Disease Control's BMI-for-Age Growth Charts. Metabolic syndrome was diagnosed when three of the five criteria were met. Data were propensity-matched and compared with NHANES (National Health and Nutrition Examination Survey), which offered a generalizable sample to the US population.
Results: Fifty-five patients under 18 years old with a diagnosis of acrochordons were mostly Caucasian (76%) and female (64%). The mean BMI was 27.3, with 49.5% categorized as obese and 20% as overweight. The mean age of diagnosis was 10.1 years. Acrochordon predominantly appeared in the axilla. In our cohort, three patients (5.5%) met the criteria for metabolic syndrome. The prevalence of obesity (42% vs. 21%), type 2 diabetes mellitus (4.8% vs. 0.6%), hyperlipidemia (8.1% vs. 0%), and hypertension (1.6% vs. 0%) was greater in our cohort compared with NHANES.
Conclusions: Like the adult population, acrochordons may serve as marker for metabolic disease in the pediatric population.
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| http://dx.doi.org/10.1111/pde.15639 | DOI Listing |
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