AI Article Synopsis
- Granulomatosis with polyangiitis (GPA) is a rare autoimmune disorder affecting mainly the respiratory system and kidneys, causing symptoms like sinusitis and rapidly progressive kidney disease.
- The disorder can also impact other body parts, including skin, eyes, heart, joints, and the nervous system.
- The text discusses two hospital cases featuring atypical symptoms like fever and renal masses, outlining the clinical progression and supporting literature on these unusual manifestations.
Article Abstract
Granulomatosis with polyangiitis (GPA) is an uncommon disorder that mainly involves the upper and lower respiratory tract and kidney, presenting as sinusitis, saddle nose, otitis media, pulmonary nodule and cavity, rapidly progressive glomerulonephritis. It also affects skin, eye, heart, joint and nervous system. Renal involvement in GPA is commonly manifested as necrotising glomerulonephritis, while renal mass is very rare. We herein present two hospitalised cases with fever, pulmonary cavity and renal mass. Clinical course and examinations of the cases, from symptoms to diagnosis, will be discussed in detail, along with a relevant literature review of this unusual renal manifestation.
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| http://dx.doi.org/10.55563/clinexprheumatol/ql3zzz | DOI Listing |
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