A higher prevalence of infections and mortality rate has been reported recently in hospital-acquired infections (HAI). The biofilm-forming capability of makes it an extremely dangerous pathogen, especially in device-associated hospital-acquired infections (DA-HAI), thereby it resists the penetration of antibiotics. Further, the transmission of the SARS-CoV-2 virus was exacerbated in DA-HAI during the epidemic. This review specifically examines the complex interconnections between several components and genes that play a role in the biofilm formation and the development of infections. The current review provides insights into innovative treatments and therapeutic approaches to combat biofilm-related infections, thereby ultimately improving patient outcomes and reducing the burden of HAI.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11290764 | PMC |
| http://dx.doi.org/10.2217/fmb-2023-0263 | DOI Listing |
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