Intracranial epidermoid cysts are benign, slow-growing congenital tumors of ectodermal origin. They are rare embryonal benign cystic masses with an incidence rate of approximately 0.04%-0.6% of intracranial tumors. Computed tomography (CT) and magnetic resonance imaging (MRI) are fundamental diagnostic tools providing valuable information for surgical management. We reported a 59-year-old male patient with right limb weakness twelve hours prior to admission, slurred speech, and paresis of the facial nerve. Based on history taking, physical examination, and radiology examinations, we concluded a diagnosis of non-communicated hydrocephalus due to a right cerebellar intra-axial tumor with a suspicion of low-grade glioma (Pylocitic Astrocytoma). CT and MRI in intracranial epidermoid cysts are fundamental diagnostic tools for diagnosing and obtaining helpful information for surgical planning. Intracranial epidermoid cysts appear as lobulated lesions filling and expanding CSF spaces and exerting a gradual mass effect, insinuating between structures and encasing adjacent nerves and vessels. In this case, we noted a hypodense lesion with irregular calcifications and well-defined on the right cerebellar region measuring 6.15 × 5.47 × 5.7 cm, surrounded by a hypodense image suggesting an intra-axial mass suspected of low-grade glioma with a differential diagnosis of brain abscess. The hypointense lesion on the T1WI sequence found in the MRI examination, with no significant contrast enhancement and restricted diffusion area on DWI, was one of the notable features described in the epidermoid cyst. Intracranial epidermoid cyst rarely occurs in the intracranial, resulting in many symptoms in this case, which should be diagnosed and treated promptly. Imaging aids in proper diagnosis and provides more valuable information for further treatment.
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http://dx.doi.org/10.1016/j.radcr.2024.03.061 | DOI Listing |
J Neurooncol
January 2025
University of Virginia, Charlottesville, VA, USA.
Background: Even a gross total resection of a benign epidermoid tumor (ET) carries a high risk of recurrence. The management strategy mostly involves redo surgical excision but at a significant cost of morbidity and mortality. The role of adjuvant radiation therapies in this scenario is still undefined.
View Article and Find Full Text PDFCureus
December 2024
Neurological Surgery, Cooper University Hospital, Camden, USA.
White epidermoid cysts are a rare type of epidermoid cyst that appears hyperintense on T1 weighted magnetic resonance imaging (MRI) and are known for their characteristic pearly white outer appearance on gross pathology. White epidermoid cysts are not common findings; therefore, this illustrative case report was written to highlight the characteristics, progression, radiological evaluation, and management of a patient who presented to our center. This case report emphasizes the importance of determining the proper diagnosis to treat and manage the condition appropriately and avoid potential future complications.
View Article and Find Full Text PDFNeurosurgery
January 2025
Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, USA.
J Clin Neurosci
January 2025
Department of Neurosurgery, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Background: Craniopharyngiomas are epithelial tumors derived from the remnants of the Rathke pouch, while Rathke cleft cysts (RCC) are benign cystic lesions originating from the Rathke pouch itself [1]. Rathke cleft cysts comprise 10-15% of the hypophyseal tumors, while craniopharyngiomas are relatively rare, comprising only 2-5% of intracranial tumors [2]. Both located in the sellar and parasellar regions and share clinical symptoms including headache, visual disturbances, and endocrine dysfunction [3].
View Article and Find Full Text PDFMed J Armed Forces India
December 2024
SSMO Neurosurgery, YCM Hospital & PGI, Pimpri, Pune, India.
Intracranial epidermoid cyst (EC) is a slow-growing, benign lesion that rarely undergoes a malignant transformation. When it does occur, the clinical course is aggressive. Certain radiological criteria may give a clue to diagnosis and help in deciding the appropriate course of action as well as prognostication.
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