Prostate Cancer Radioligand Therapy: Beta-labeled Radiopharmaceuticals.

PET Clin

Department of Biophysics and Nuclear Medicine, Hadassah Medical Organization, Jerusalem, Israel; Hebrew University of Jerusalem, Jerusalem, Israel; University College London, London, UK.

Published: July 2024

Prostate cancer is the most common malignancy in men worldwide, with an estimated 174,650 new cases per year in the United States, and the second cancer-related cause of death, after lung cancer, with 31,620 deaths per year. While the 5 year survival rate for prostate cancer in patients without metastatic spread is nearly 100%, those with distant metastases have 5 year survival rates of approximately 30%. Initial diagnosis and assessment are based on PSA levels, Gleason score (derived from prostate biopsy), and advanced imaging modalities, including prostate MR imaging and PSMA-PET/computed tomography in patients with high-risk features.

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http://dx.doi.org/10.1016/j.cpet.2024.03.011DOI Listing

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