AI Article Synopsis
- - Peripheral precocious puberty (PPP) is the early sexual maturation that occurs without influence from the central nervous system.
- - Diagnosis involves identifying the underlying causes, which can be congenital or acquired, and requires hormonal tests, imaging, and sometimes genetic analysis.
- - There are effective treatments for almost all forms of PPP, and ongoing research aims to improve these treatments and enhance our understanding of the underlying mechanisms.
Article Abstract
Peripheral precocious puberty (PPP) refers to the early onset of sexual maturation that is independent of central nervous system control. The extensive differential diagnosis includes congenital and acquired causes. Presenting features depend on which class of sex steroids is involved, and diagnosis rests on hormonal and, if indicated, imaging and/or genetic studies. Effective treatment exists for nearly all causes of PPP. Ongoing research will advance our therapeutic armamentarium and understanding of the pathophysiologic basis of these conditions.
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| http://dx.doi.org/10.1016/j.ecl.2024.01.006 | DOI Listing |
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