Purpose: Septoplasty and rhinoplasty are common otolaryngological procedures, often combined as septorhinoplasty (SRP), offering aesthetic and functional benefits. These surgeries are believed to potentially risk postoperative infections due to natural bacterial flora in the nares. This study evaluates the effectiveness of prophylactic antibiotics in reducing post-surgical infection complications.
Materials And Methods: A systematic review was conducted using PubMed, Cochrane, and Web of Science, adhering to PRISMA guidelines, focusing on antibiotic use in septoplasty, rhinoplasty, and SRP. The study included randomized control trials, single/double-blind studies, retrospective chart reviews, and prospective cohort studies, excluding pediatric, non-human research, or studies with inaccessible data. Postoperative infection rates were analyzed utilizing R software as a form of Statistic.
Results: From 697 articles, 15 studies were chosen for meta-analysis, involving 2225 patients, with 1274 receiving prophylactic antibiotics and 951 as controls. The meta-analysis indicated an odds ratio of 0.65 (95 % CI: [0.23, 1.89]), showing no significant protective effect of prophylactic antibiotics.
Discussion: The study found no significant infection rate reduction with prophylactic antibiotic use. Notable were inconsistencies in study designs, antibiotic administration timing, and varied surgical practices. Antibiotic use risks were considered. Study limitations include potential biases and the retrospective nature of many studies.
Conclusions: This review and meta-analysis found no substantial evidence supporting prophylactic antibiotics' effectiveness in reducing postoperative infection rates in septoplasty, rhinoplasty, and SRP, indicating a need to reevaluate practices and develop evidence-based guidelines. Future research should focus on comprehensive, randomized control studies, covering both preoperative and postoperative stages.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.amjoto.2024.104333 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparison on functional and esthetic outcomes between single and combined surgery to crooked nose deformities.
J Plast Reconstr Aesthet Surg
November 2024
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Taoyuan, Taiwan. Electronic address:
Background: Nose deviation deformities pose a complex cosmetic and functional problem. The most common surgical intervention to manage such deformities is septorhinoplasty, typically performed by a plastic surgeon or a rhinologist. This study investigated the effect of a combined operation by a plastic surgeon and rhinologist, comparing them with those operations performed singlehandedly by a plastic surgeon.
View Article and Find Full Text PDFSecondary cleft lip rhinoplasty. Our experience of two decades.
Ann Chir Plast Esthet
December 2024
Department of Plastic, Reconstructive and Aesthetic Surgery, AP-HM, Conception University Hospital, 147, boulevard Baille, 13005 Marseille, France.
Patients who underwent cleft lip surgery in childhood may develop nasal malformation later in life. Various procedures have been described to correct these malformations. This study aims to describe our surgical approach and assess the morphometric outcomes of secondary cleft-lip rhinoplasty performed at the plastic surgery department in Marseille between 2002 and 2022.
View Article and Find Full Text PDFNasal breathing: a neglected factor in metabolic regulation?
Eur Arch Otorhinolaryngol
December 2024
Otorhinolaryngology and Head & Neck Surgery, Centro Hospitalar Universitário de Santo António, Largo do Prof. Abel Salazar, 4099-001, Porto, Portugal.
Article Synopsis
An Algorithmic Approach to use Extended Spreader Grafts in Deviated Noses.
Aesthetic Plast Surg
November 2024
Department of Plastic surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan.
Background: Restoration of a straight and adequately wide nasal dorsum is challenging in patients with deviated noses. Supporting a reformed septum with an extended spreader graft (ESG) is important for maintaining position.
Objective: The study aimed to describe different types of ESG and propose a comprehensive algorithm for using specific types of ESGs in rhinoplasty according to the particular type of deviated nose.
The benefits of septoplasty for patients with deviated nasal septum and allergic rhinitis: a meta-analysis.
Sci Rep
November 2024
Department of Otolaryngology, Head and Neck Surgery, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, 130000, Jilin Province, China.
Article Synopsis
- A study assessed the effectiveness of endoscopic septoplasty for patients with a deviated nasal septum and allergic rhinitis, using a meta-analysis of various databases up to 2024.
- Results showed that patients who underwent the surgery experienced significant improvement in total nasal symptoms and specific allergic rhinitis symptoms compared to those treated with spray therapy alone.
- The study concluded that while septoplasty provides substantial benefits, it should be conducted by skilled clinicians who can evaluate the individual anatomy of the patient's nasal septum.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!