A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_session59vimhujc68ji9ri0qjrq8aotm23tm91): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

Achilles' heel of male infertility: good LEGO players. | LitMetric

Achilles' heel of male infertility: good LEGO players.

J Assist Reprod Genet

Department of Urology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310005, China.

Published: June 2024

In a recent journal article, Chen et al. identified a germ cell-specific cofactor, STYXL1, associated with male fertility function. Deletion of STYXL1 prevents the LEGO player CCT complex from properly folding key microtubule proteins of the sperm flagellum, which affects sperm motility and male fertility function.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11224056PMC
http://dx.doi.org/10.1007/s10815-024-03122-9DOI Listing

Publication Analysis

Top Keywords

male fertility
8
fertility function
8
achilles' heel
4
heel male
4
male infertility
4
infertility good
4
good lego
4
lego players
4
players journal
4
journal article
4

Similar Publications

Introduction: Klinefelter syndrome (KS) is a genetic condition characterised by the presence of an extra X chromosome in males (47,XXY). KS is associated with various phenotypic characteristics in adult life, including infertility, hypogonadism and increased risk of type II diabetes, cardiovascular disease and osteoporosis. Additionally, individuals with KS often experience mental health challenges and functional impairments that significantly impact their quality of life.

View Article and Find Full Text PDF

Objective: Despite guidelines indicating no contraindications for contraceptives in women with inflammatory bowel disease (IBD), this population shows increased voluntary childlessness and lower contraceptive use. Knowledge gaps among healthcare providers on IBD's impact on fertility and contraception may drive these trends. This survey assessed knowledge discrepancies among IBD patients, gastroenterologists (GEs), and women's healthcare providers (WHPs) regarding fertility and contraception.

View Article and Find Full Text PDF

Challenges in bird cryopreservation.

Cryo Letters

March 2025

Departamento de Produccion Agrícola y Animal, Universidad Autonoma Metropolitana Unidad Xochimilco Calzada del Hueso 1100 Coyoacan, 04960 Ciudad de Mexico, Mexico. and

Cryopreservation is a fundamental technique for preserving the structural and functional integrity of biological material, particularly for the conservation of genetic resources in avian species. Since its development in the 1940s, this technology has advanced significantly, although challenges persist, primarily due to the unique morphology of avian sperm, which complicates cryoprotectant penetration and increases the risk of structural damage. Overcoming these challenges is crucial for improving semen preservation, supporting the sustainability of avian species, and contributing to conservation efforts.

View Article and Find Full Text PDF

Do weakly deleterious mutations contribute to the reproductive and health challenges of bottlenecked species? Peers et al. (2025) investigated the role of prolonged low effective population size in cheetahs (Acinonyx jubatus) and its implications in the accumulation of pseudogenes. They identified 65 cheetah-specific premature termination codons, four of which (DEFB116, ARL13A, CFAP119, and NT5DC4) were linked to male fertility and immune deficiencies.

View Article and Find Full Text PDF

Misinformation about COVID-19 vaccines has hampered their uptake worldwide. In Ghana, a belief that COVID-19 vaccines affect fertility is prevalent and difficult to counter. UNICEF Ghana co-produced a context-driven, behavioral science-based audio drama ('A shot of love') that aimed to debunk this misinformation narrative.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!