AI Article Synopsis
- This study investigates how serum calcium (SC) levels relate to the occurrence of postoperative atrial fibrillation (POAF) in patients undergoing heart surgery.
- It analyzed data from over 12,000 patients, revealing that those with low SC levels had a significantly higher rate of POAF compared to those with normal levels.
- The findings suggest that low SC levels are a risk factor for POAF, regardless of other factors like age, sex, and pre-existing health conditions.
Article Abstract
Objectives: This study aims to investigate the relationship between serum calcium (SC) levels and the incidence of postoperative atrial fibrillation (POAF) in patients undergoing coronary artery bypass graft surgery.
Methods: This retrospective, observational cohort study consecutively enrolled patients undergoing isolated coronary artery bypass grafting in Beijing Anzhen Hospital from January 2018 to December 2021. Patients with a previous history of atrial fibrillation or atrial flutter or requiring concomitant cardiac surgery were excluded. A logistic regression model was used to determine predictors of POAF. Multivariable adjustment, inverse probability of treatment weighting and propensity score matching were used to adjust for confounders. Moreover, we conducted univariable and multivariable logistic regression analyses on preoperative and postoperative SC and ionized SC levels.
Results: The analysis encompassed 12 293 patients. The POAF rate was significantly higher in patients with low SC level than those without (1379 [33.9%] vs 2375 [28.9%], P < 0.001). Low SC level was associated with an increased odds ratio of POAF (odds ratio [95% confidence interval]: 1.27 [1.18-1.37], P < 0.001). Inverse probability of treatment weighting and propensity score matching analyses confirmed the results. The increased POAF rate in low SC level group still existed among subgroup analysis based on different age, sex, body mass index, hypertension, hyperlipidaemia, CHA2DS2-VASc and magnesium.
Conclusions: Low SC level indicates elevated POAF risk in patients undergoing isolated coronary artery bypass graft surgery even after the adjustment for age, sex, cardiovascular risk factors, echocardiographic parameters and laboratory markers.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11082466 | PMC |
| http://dx.doi.org/10.1093/icvts/ivae077 | DOI Listing |
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