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Sosuga Virus Detected in Egyptian Rousette Bats () in Sierra Leone. | LitMetric

AI Article Synopsis

  • The Sosuga virus (SOSV) is a rare paramyxovirus linked to human illness, first identified in 2012 in an individual from South Sudan and Uganda.
  • Ecological studies revealed that the Egyptian rousette bat (ERB) is the only bat species consistently testing positive for SOSV, indicating it serves as a competent host for the virus.
  • Recent surveillance in Sierra Leone identified SOSV RNA in ERBs, suggesting that the virus has expanded its range from East Africa to West Africa, potentially affecting ERB populations across sub-Saharan Africa.

Article Abstract

Sosuga virus (SOSV), a rare human pathogenic paramyxovirus, was first discovered in 2012 when a person became ill after working in South Sudan and Uganda. During an ecological investigation, several species of bats were sampled and tested for SOSV RNA and only one species, the Egyptian rousette bat (ERBs; ), tested positive. Since that time, multiple other species have been sampled and ERBs in Uganda have continued to be the only species of bat positive for SOSV infection. Subsequent studies of ERBs with SOSV demonstrated that ERBs are a competent host for SOSV and shed this infectious virus while exhibiting only minor infection-associated pathology. Following the 2014 Ebola outbreak in West Africa, surveillance efforts focused on discovering reservoirs for zoonotic pathogens resulted in the capture and testing of many bat species. Here, SOSV RNA was detected by qRT-PCR only in ERBs captured in the Moyamba District of Sierra Leone in the central region of the country. These findings represent a substantial range extension from East Africa to West Africa for SOSV, suggesting that this paramyxovirus may occur in ERB populations throughout its sub-Saharan African range.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11054331PMC
http://dx.doi.org/10.3390/v16040648DOI Listing

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