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Gestational Diabetes and the Gut Microbiota: Fibre and Polyphenol Supplementation as a Therapeutic Strategy. | LitMetric

Gestational Diabetes and the Gut Microbiota: Fibre and Polyphenol Supplementation as a Therapeutic Strategy.

Microorganisms

Department of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria 0028, South Africa.

Published: March 2024

AI Article Synopsis

  • Gestational diabetes mellitus (GDM) poses significant health risks for both mothers and children, prompting interest in preventive strategies.
  • Research indicates that an imbalance in gut microbiota is linked to GDM, suggesting dietary changes could help address this issue.
  • Diets rich in fiber and polyphenols may enhance gut health, reduce inflammation, and support better overall metabolic function, making them potential aids in GDM prevention.

Article Abstract

Gestational diabetes mellitus (GDM) is an escalating public health concern due to its association with short- and long-term adverse maternal and child health outcomes. Dysbiosis of microbiota within the gastrointestinal tract has been linked to the development of GDM. Modification of microbiota dysbiosis through dietary adjustments has attracted considerable attention as adjunct strategies to improve metabolic disease. Diets high in fibre and polyphenol content are associated with increased gut microbiota alpha diversity, reduced inflammation and oxidative processes and improved intestinal barrier function. This review explores the potential of fibre and polyphenol supplementation to prevent GDM by investigating their impact on gut microbiota composition and function.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11051981PMC
http://dx.doi.org/10.3390/microorganisms12040633DOI Listing

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