AI Article Synopsis
- Chronic lateral epicondylitis is a pain condition that is not fully understood, potentially involving neuropathic pain and sensitization, with botulinum toxin being a potential treatment option for managing pain and function.
- A literature search identified 14 studies exploring botulinum toxin injections targeting either the tendon or specific extensor muscles involved in the condition.
- The findings suggest that treatment should shift focus from the affected tendon to the surrounding muscles to prevent ongoing issues, with details shared about injection methods, dosages, timing, and potential side effects.
Article Abstract
Background: Chronic lateral epicondylitis challenges the therapeutical approach; underlying mechanisms are incompletely understood; neuropathic pain and central and peripheral sensitization may explain the fact that botulinum toxin has been found to play a role in pain and function management.
Methods: We searched the literature for MeSH terms: lateral epicondylitis or synonyms and botulinum toxin.
Results: We found 14 papers containing trials on botulinum toxin injection into the tendon or into the extensor muscles (specifically, extensor carpi radialis brevis and extensor communis digitorum). We followed the administration pathways, doses, timing, and side effects.
Conclusions: With a chronic course, the focus of the therapy shifts from the afflicted tendon to the inserting muscles, as muscle contracture may create a vicious loop to perpetuate and aggravate the disease. Doses, timing, and side effects are discussed.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11050841 | PMC |
| http://dx.doi.org/10.3390/life14040528 | DOI Listing |
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