This study investigated antimicrobial resistance in Salmonella enterica serovar Choleraesuis (S. Choleraesuis) isolates from diseased pigs in Taiwan (2015-2020). Among 272 isolates, florfenicol (96.7%), enrofloxacin (96.3%), doxycycline (91.2%), gentamicin (84.6%), and tiamulin (80.5%) exhibited high resistance. 99.3% of the isolates were resistant to at least one antibiotic, and 97.8% of the isolates were multidrug resistant. This study illustrated that S. Choleraesuis isolates exhibited high resistance to antimicrobials currently used in the Taiwanese swine industry.
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http://dx.doi.org/10.1016/j.jmii.2024.04.005 | DOI Listing |
Gut Microbes
November 2024
College of Veterinary Medicine, Southwest University, Beibei, Chongqing, China.
Non-typhoidal (NTS) is a major global foodborne pathogen that poses a major public health concern worldwide, and no vaccines are available for protecting against infection of multiple serotypes, therefore, the development of vaccines to provide broad protection is valuable. In this work, we aimed to regulate lipopolysaccharide (LPS) synthesis of live for exposing conserved protein antigens on the outer membrane while maintaining smooth LPS patterns to keep their original ability to invade host cells for inducing cross-protection against infection of multiple serotypes. We generated a series of mutants defective in genes to affect the length of LPS.
View Article and Find Full Text PDFIJID Reg
June 2024
Center for Diagnostics and Vaccine Development, Centres for Disease Control, Taichung, Taiwan.
Objectives: , a zoonotic pathogen, significantly impacts global human health. Understanding its serotype distribution and antimicrobial resistance is crucial for effective control measures and medical interventions.
Methods: We collected isolates and demographic data from Taiwanese hospitals between 2004 and 2022, analyzing their serotypes and antimicrobial susceptibility.
Nat Food
May 2024
Key Laboratory of Alkene-Carbon Fibres-Based Technology & Application for Detection of Major Infectious Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Pasteurien College, Suzhou Medical College, Soochow University, Suzhou, China.
J Microbiol Immunol Infect
August 2024
Department of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan; Animal Disease Diagnostic Center, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan; Sustainable Swine Research Center, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan. Electronic address:
This study investigated antimicrobial resistance in Salmonella enterica serovar Choleraesuis (S. Choleraesuis) isolates from diseased pigs in Taiwan (2015-2020). Among 272 isolates, florfenicol (96.
View Article and Find Full Text PDFJ Infect Chemother
November 2024
Department of Infectious Diseases, Medical Mycology Research Center, Chiba University, Chiba, 260-8673, Japan.
Salmonella enterica subspecies enterica serovar Choleraesuis (S. Choleraesuis) is a nontyphoidal Salmonella pathogen that causes swine paratyphoids. S.
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