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http://dx.doi.org/10.1053/j.jfas.2023.11.006 | DOI Listing |
Nat Commun
January 2025
Department of Machine Learning, Moffitt Cancer Center, Tampa, FL, USA.
AI decision support systems can assist clinicians in planning adaptive treatment strategies that can dynamically react to individuals' cancer progression for effective personalized care. However, AI's imperfections can lead to suboptimal therapeutics if clinicians over or under rely on AI. To investigate such collaborative decision-making process, we conducted a Human-AI interaction study on response-adaptive radiotherapy for non-small cell lung cancer and hepatocellular carcinoma.
View Article and Find Full Text PDFJ Mol Diagn
February 2025
Daiichi Sankyo, Inc., Basking Ridge, New Jersey.
This study demonstrates the analytical and clinical validity of the approved (United States and Japan) plasma-based Guardant360 companion diagnostic (CDx) test for selecting patients with human epidermal growth factor receptor 2 (HER2 [ERBB2])-mutated (HER2m) non-small-cell lung cancer (NSCLC) for trastuzumab deruxtecan (T-DXd) treatment. Concordance between the Guardant360 CDx test and the plasma-based AVENIO ctDNA Expanded Kit Assay (AVENIO), as well as the tissue-based clinical trial assays (CTAs) was investigated. Clinical utility was assessed by comparing T-DXd clinical efficacy results of patients in DESTINY-Lung01/02 who tested positive for HER2 mutations using the Guardant360 CDx test to benchmark efficacy results from DESTINY-Lung01/02.
View Article and Find Full Text PDFEndoscopy
January 2025
Gastroenterology and Hepatology, Amsterdam UMC Location VUmc, Amsterdam, Netherlands.
Background: Patient experience is a fundamental element of colonoscopy. The Gloucester Comfort Scale (GCS) is used by clinicians to report patient comfort. However, insights regarding the extent to which clinician-reported GCS scores represent the patient's experience are lacking.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
January 2025
Department of Obstetrics & Gynecology, University Hospital of Ioannina, Ioannina, Greece. Electronic address:
Objective: To evaluate the amount and types of physical activity (PA) performed by Greek women during pregnancy and assess the validity and reliability of the Greek version of the Pregnancy Physical Activity Questionnaire (PPAQ).
Study Design: This prospective study comprised two stages. The first stage was the completion of the PPAQ Greek version twice, with a one-week interval between the two rounds, to assess internal consistency and reproductivity.
Integr Environ Assess Manag
January 2025
Faculty of Fine Arts, Design and Architecture Department of Landscape Architecture, Tekirdağ Namık Kemal University, Tekirdağ, Türkiye.
Wetlands provide necessary ecosystem services, such as climate regulation and contribution to biodiversity at global and local scales, and they face spatial changes due to natural and anthropogenic factors. The degradation of the characteristic structure signals potential severe threats to biodiversity. This study aimed to monitor the long-term spatial changes of the Göksu Delta, a critical Ramsar site, using remote sensing techniques.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!