The phrase "Bench-to-Bedside" is a well-known phrase in medicine, highlighting scientific discoveries that directly translate to impacting patient care. Key examples of translational research include identification of key molecular targets in diseases and development of diagnostic laboratory tests for earlier disease detection. Bridging these scientific advances to the bedside/clinic has played a meaningful impact in numerous patient lives. The spaceflight environment poses a unique opportunity to also make this impact; the nature of harsh extraterrestrial conditions and medically austere and remote environments push for cutting-edge technology innovation. Many of these novel technologies built for the spaceflight environment also have numerous benefits for human health on Earth. In this manuscript, we focus on "Spaceflight-to-Eye Clinic" and discuss technologies built for the spaceflight environment that eventually helped to optimize ophthalmic health on Earth (e.g., LADAR for satellite docking now utilized in eye-tracking technology for LASIK). We also discuss current technology research for spaceflight associated neuro-ocular syndrome (SANS) that may also be applied to terrestrial ophthalmic health. Ultimately, various advances made to enable to the future of space exploration have also advanced the ophthalmic health of individuals on Earth.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.lssr.2024.02.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of an Aerial Manipulation System Using Onboard Cameras and a Multi-Fingered Robotic Hand with Proximity Sensors.
Sensors (Basel)
January 2025
Department of Mechanical and Intelligent Systems Engineering, The University of Electro-Communications, Tokyo 1828585, Japan.
Recently, aerial manipulations are becoming more and more important for the practical applications of unmanned aerial vehicles (UAV) to choose, transport, and place objects in global space. In this paper, an aerial manipulation system consisting of a UAV, two onboard cameras, and a multi-fingered robotic hand with proximity sensors is developed. To achieve self-contained autonomous navigation to a targeted object, onboard tracking and depth cameras are used to detect the targeted object and to control the UAV to reach the target object, even in a Global Positioning System-denied environment.
View Article and Find Full Text PDFSpatial Characterization of Woody Species Diversity in Tropical Savannas Using GEDI and Optical Data.
Sensors (Basel)
January 2025
Forest Biometrics and Remote Sensing Laboratory (Silva Lab), School of Forest, Fisheries, and Geomatics Sciences, University of Florida, P.O. Box 110410, Gainesville, FL 32611, USA.
Developing the capacity to monitor species diversity worldwide is of great importance in halting biodiversity loss. To this end, remote sensing plays a unique role. In this study, we evaluate the potential of Global Ecosystem Dynamics Investigation (GEDI) data, combined with conventional satellite optical imagery and climate reanalysis data, to predict in situ alpha diversity (Species richness, Simpson index, and Shannon index) among tree species.
View Article and Find Full Text PDFIntegrated Proteomic and Metabolomic Analysis of Muscle Atrophy Induced by Hindlimb Unloading.
Biomolecules
December 2024
Department of Aerospace Medical Training, School of Aerospace Medicine, Fourth Military Medical University, Xi'an 710032, China.
Skeletal muscle atrophy, which is induced by factors such as disuse, spaceflight, certain medications, neurological disorders, and malnutrition, is a global health issue that lacks effective treatment. Hindlimb unloading is a commonly used model of muscle atrophy. However, the underlying mechanism of muscle atrophy induced by hindlimb unloading remains unclear, particularly from the perspective of the myocyte proteome and metabolism.
View Article and Find Full Text PDFProximal remote sensing: an essential tool for bridging the gap between high-resolution ecosystem monitoring and global ecology.
New Phytol
January 2025
Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, 91011, USA.
A new proliferation of optical instruments that can be attached to towers over or within ecosystems, or 'proximal' remote sensing, enables a comprehensive characterization of terrestrial ecosystem structure, function, and fluxes of energy, water, and carbon. Proximal remote sensing can bridge the gap between individual plants, site-level eddy-covariance fluxes, and airborne and spaceborne remote sensing by providing continuous data at a high-spatiotemporal resolution. Here, we review recent advances in proximal remote sensing for improving our mechanistic understanding of plant and ecosystem processes, model development, and validation of current and upcoming satellite missions.
View Article and Find Full Text PDFExposure to spaceflight enhances the virulence of Purpureocillium lilacinum against Tetranychus cinnabarinus: modulation of the host's enzyme activities and microbiome.
Arch Microbiol
January 2025
Engineering Research Center of Biological Control, Ministry of Education and Guangdong Province, South China Agricultural University, Guangzhou, 510642, China.
Multiple studies have been conducted to investigate the impact of space conditions on human, plant, and microbial life. This research investigated the virulence of spaceflight mutants of the entomopathogenic fungus Purpureocillium lilacinum (HP7, HP36, HP52) and its original strain (SP535) against Tetranychus cinnabarinus as well as examination of the T. cinnabarinus immune response, including alterations in enzyme profiles and microbiome composition post fungal application.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!