AI Article Synopsis
- Plasmonic Au@Ag core-shell nanoisland films (Au@AgNIFs) were created on a glass substrate using a seed-mediated growth method, with their structure confirmed by various microscopy techniques.
- The films exhibited broad UV-Vis absorption and could reach temperatures of 66.9 °C under sunlight, effectively eradicating bacteria through photothermal therapy.
- Additionally, Au@AgNIFs enhanced Raman signals for detection, showcasing their potential for combined bacterial treatment and diagnostics (theranostics).
Article Abstract
Plasmonic metal nanomaterials have been extensively investigated for their utilizations in biomedical sensing and treatment. In this study, plasmonic Au@Ag core-shell nanoisland films (Au@AgNIFs) were successfully grown onto a glass substrate using a seed-mediated growth procedure. The nanostructure of the Au@AgNIFs was confirmed through scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and atomic force microscopy (AFM). The UV-Vis spectra of the Au@AgNIFs exhibited a broad absorption in the visible range from 300 to 800 nm because of the surface plasmon absorption. Under simulated sunlight exposure, the temperature of optimal Au@AgNIF was increased to be 66.9 °C to meet the requirement for photothermal bacterial eradication. Furthermore, the Au@AgNIFs demonstrated a consistent photothermal effect during the cyclic on/off exposure to light. For photothermal therapy, the Au@AgNIFs revealed superior efficiency in the photothermal eradication of () and (). With their unique nanoisland nanostructure, the Au@AgNIFs exhibited excellent growth efficiency of bacteria in comparison with that of the bare glass substrate. The Au@AgNIFs were also validated as a surface-enhanced Raman scattering (SERS) substrate to amplify the Raman signals of and . By integrating photothermal therapy and SERS detection, the Au@AgNIFs were revealed to be a potential platform for bacterial theranostics.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11053632 | PMC |
| http://dx.doi.org/10.3390/nano14080695 | DOI Listing |
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